Searchable abstracts of presentations at key conferences in endocrinology

ea0028p102 | Clinical practice/governance and case reports | SFEBES2012

The economics of the treatment of Grave’s disease; different medication regimes, a cost-benefit analysis

Grant Paul , Haq Masud

There are traditionally two major methods of treating autoimmune biochemical hyperthyroidism (Grave's disease) with anti-thyroid medication employed by Endocrinologist's in the UK today. The first is ‘dose titration’ and the second is ‘block and replace’, each treatment regime has it's own advantages and disadvantages and there is sometimes controversy over which is the best approach. A Cochrane review in 2005, undertook a systematic evaluation of all the g...

ea0018p3 | (1) | MES2008

A genetic cause for primary amenorrhoea

Martineau Marcus , Haq Masud

Primary Amenorrhoea is usually the result of a genetic or anatomical abnormality. Androgen insensitivity syndrome (AIS) is an uncommon cause in which individuals with a 46XY male karyotype are resistant to testosterone due to a defect of the androgen receptor.A 16-year-old female of non-consanguineous parents presented with primary amenorrhoea. There was no family history of delayed puberty. She was of normal female appearance (height 5′9″, B...

ea0015p31 | Clinical practice/governance and case reports | SFEBES2008

Osteomalacia with associated functional hypoparathyroidism

El-Gayar Heba , Haq Masud

Osteomalacia is most commonly caused by vitamin D deficiency. This typically results in features of secondary hyperparathyroidism and hypophosphataemia. PTH secretion is however dependant on normal serum magnesium levels. Hypomagnesaemia due to malabsorption, diuretic or laxative abuse may lead to functional hypoparathyroidism despite typical features of osteomalacia.A 24-year old Afro-Caribbean woman presented with bilateral knee and upper back pain wit...

ea0034p370 | Steroids | SFEBES2014

A very late and unusual presentation of congenital adrenal hyperplasia

Abou-Saleh Ahmad , Barnes Dennis , Haq Masud

A 71-year-old gentleman was referred for investigation of bilateral enlarged adrenals first discovered after presenting with subacute bowel obstruction. A CT scan of his abdomen revealed the left adrenal was 8×5 cm, the right 3 cm. No other abnormalities were detected.The patient was otherwise well. No other medical history was volunteered. On examination, he was of short stature (height 1.47 m) with a normal pattern of pubic and axillary hair. Bloo...

ea0025p138 | Diabetes, metabolism and cardiovascular | SFEBES2011

Hypogonadism with subsequent multi-organ involvement: a mystery solved

Mohandas Cynthia , Barnes Dennis , Harrington Derek , Haq Masud

A 53-year-old gentleman was seen following a recent diagnosis of type 2 diabetes in May 2009. He had suffered a subarachnoid haemorrhage in 1993 and remained under the local tertiary centre after developing secondary hypogonadism treated with testosterone replacement. The cause had never been established.The patient had previously been diagnosed with seronegative HLA B27 arthropathy and in December 2008 was admitted with acute cardiac failure and atrial ...

ea0055oc3 | National Clinical Cases | SFEEU2018

Hyperprolactinaemia resistant to dopamine agonist due to an ectopic source of prolactin arising from a Uterine Tumour Resembling Ovarian Sex Cord Tumours (UTROCST)

Bakhit Mohamed , Arshad Sobia , Bidmead John , Haq Masud , Lewis Dylan , Diaz-Cano Salvador , Aylwin Simon J. B.

Introduction: Moderate hyperprolactinaemia occurring in a patient with a normal pituitary MRI, assuming macroprolactin and stress are excluded, is generally considered to be due to a lesion below the level of detection of the MRI scanner. Most patients with mild-moderate hyperprolactinaemia and a normal MRI respond to dopamine agonist therapy. We describe a patient who had prolactin elevation typical of a prolactin-secreting macroadenoma, but with a normal MRI, and in whom the...