Endocrine Abstracts

Objectives: The IMPACT Survey explored self- and proxy-reported experiences of the clinical, humanistic, and economic impact of osteogenesis imperfecta (OI), a rare hereditary connective tissue disorder associated with low bone mass, bone fragility and variable secondary features. While the risk of fractures in children with OI has been well documented in previous studies, this analysis explores the prevalence and impact of OI-related clinical signs, symptoms and events (SSEs)...