Searchable abstracts of presentations at key conferences in endocrinology

ea0081ep36 | Adrenal and Cardiovascular Endocrinology | ECE2022

Evaluation of the efficacy of osilodrostat in five patients with Cushing’s syndrome: A single-center study

Hashimoto Naoko , Kono Satomi , Kono Takashi , Akira Shimatsu , Pedroncelli Alberto , Tanaka Tomoaki

Context: Osilodrostat (Osi), a potent inhibitor of 11β-hydroxylase, blocks the conversion of 11-deoxycortisol to cortisol and improves hypercortisolism in patients with Cushing’s syndrome (CS). Here, we report a study evaluating the efficacy of Osi in five non-Cushing’s disease (CD) CS patients treated with Osi in Japan.Subjects and Results: Five patients with non-CD CS were treated with Osi at Chiba University [primary disease breakdown: ...