Endocrine Abstracts

IntroductionSarcoidosis is a multisystem disorder, characterised by the presence of non-caseating granulomas. 5–13% of cases involve the nervous system. Neurosarcoidosis carries a poor prognosis and can lead to an infiltrative process in the hypothalamo-hypophyseal region, resulting in panhypopituitarism and central diabetes insipidus (DI). These are rare but serious complications of neurosarcoidosis.Case<p class="abstext"...

Introduction: Gestational diabetes mellitus (GDM) is a common condition of pregnancy, associated with significant maternal and fetal complications. Debate surrounds screening practices, without worldwide consensus on the optimal screening method. Both the one-step (a fasting two-hour 75g oral glucose tolerance test) and two-step (a non-fasting one-hour 50g glucose challenge test followed, if positive, by a fasting three-hour 100g glucose tolerance test) methods are internation...

Background: Vitamin D insufficiency and low bone mineral density (BMD) are common in primary hyperparathyroidism (PHPT). The relationship between Vitamin D status and parathyroid bone disease is worthy of investigation.Aim: Our aim was to review the medical management of PHPT in an Irish university hospital and perform a sub-group analysis on people with low BMD and vitamin D insufficiency – serum 25OH vitamin D <75 nmol/l (Evaluation and Manage...