Searchable abstracts of presentations at key conferences in endocrinology

ea0049ep963 | Pituitary - Clinical | ECE2017

Infundibular lesion presenting with central diabetes insipidus and hypogonadism

Bagir Gulay Simsek , Haydardedeoglu Filiz Eksi , Bakiner Okan , Bozkirli Emre , Ertorer M Eda

Introduction: Pituitary stalk lesions fall into three categories: congenital and developmental (rathke cleft cyst, ectopic neurohypophysis), inflammatory and infectious (hypophysitis, sarcoidosis, tuberculosis), and neoplastic (Langerhans cell histiocytosis, germinoma, metastatic tumors). Herein, we report a case with infundibular lesion presenting with central diabetes insipidus and hypogonadism.Case report: A 27-years old woman was admitted to our clin...

ea0049ep969 | Pituitary - Clinical | ECE2017

A case with headache and pitosis: pituitary macroadenoma or ophtalmoplegic migraine?

Haydardedeoglu Filiz Eksi , Bagir Gulay Simsek , Bakiner Okan , Bozkirli Emre , Ertorer Melek Eda

Case: A 28-year old man was admitted to our hospital with complaints of three days of severe headache, diplopia and ptosis of the right eye. He had pituitary macroadenoma and had been on cabergolin 0.25 mg/week for the last six months. At physical examination, he demonstrated ptosis and inability to move the right eye medially. Magnetic resonance imaging showed a 13×12 mm pituitary mass with suprasellar extension and hemorrhage. Visual field analysis was abnormal except t...

ea0041ep291 | Clinical case reports - Pituitary/Adrenal | ECE2016

Radiotherapy for nasopharyngeal carcinoma: a rare cause of hypopituitarism

Haydardedeoglu Filiz Eksi , Bagir Gulay Simsek , Bozkirli Emre , Bakiner Okan , Ertorer Melek Eda

Introduction: Radiotherapy to the head and neck area is the standard therapy used for the treatment of nasopharyngeal carcinoma. Hypopituitarism is a well-known late complication of cranial radiotherapy. Although very rarely, it may be observed following radiotherapy to the head and neck area, as well.Case report: A 53-year-old man was referred to our endocrinology department for hyponatremia and low free thyroxine (T4) with normal thyroid- st...

ea0022p155 | Cardiovascular endocrinology and lipid metabolism | ECE2010

Increased plasma viscosity is a predictor of high cardiovascular risk in women with PCOS

Haydardedeoglu Filiz Eksi , Ertorer Melek Eda , Haydardedeoglu Bulent , Kozanoglu Ilknur , Anaforoglu Inan , Tutuncu Neslihan Bascil

Introduction: Polycystic ovary syndrome (PCOS) is a common endocrinopathy that affects 5–10% of women of reproductive age. It is now recognized as not only a reproductive but also a metabolic disorder with co-morbidities, such as; diabetes, dyslipidemia, hypertension, etc. All these metabolic abnormalities predispose women with PCOS to atherosclerosis. Plasma viscosity is a major determinant of blood flow in microcirculation. Preliminary data indicate that elevated plasma...

ea0016p392 | Neuroendocrinology | ECE2008

Macroprolactinemia seems to have a positive effect on platelet activation through ADP stimulation

Anaforoglu Inan , Ertorer Eda , Kozanoglu Ilknur , Unal Birsel , Haydardedeoglu Filiz , Tutuncu Neslihan Bascil , Demirag Nilgun Guvener

Objective: Platelet activation is a recently recognized characteristic of prolactin, which functions through the potentiation of ADP-induced P-selectin expression on platelets. Studies in hyperprolactinemic patients demonstrated atherosclerotic disorders related to insulin resistance; convenient milieus for platelet activation. To investigate the association between hyperprolactinemia and platelet activation related to P-selectin expression, we studied on hyperprolactinemic an...

ea0056p371 | Diabetes (to include epidemiology, pathophysiology) | ECE2018

A difficult synchronous diagnosis; Type 2 Diabetes and insulinoma

Sefa Bakiner Okan , Bozkirli Emre , Haydardedeoglu Filiz Eksi , Bagir Gulay Simsek , Ertorer Melek Eda

Background: In the literature there are rare cases of patients with known Type 2 Diabetes Mellitus whom are diagnosed as insulinoma. However a synchronous diagnosis with insulinoma and diabetes for a patient presenting with hypoglycemia symptoms is not an expected condition.Case: A 79 years-old female patient was sent to our Endocrinology outpatient clinic because of repeating minor and major hypoglycemia attacks. She had no important finding in her back...

ea0056p372 | Diabetes (to include epidemiology, pathophysiology) | ECE2018

Immunoglobulin G4 related pancreatitis; can it be a rare cause of secondary diabetes?

Bozkirli Emre , Bakiner Okan Sefa , Bagir Gulay Simsek , Haydardedeoglu Filiz Eksi , Ertorer Melek Eda

Background: Autoimmune pancreatitis (AIP) is a relatively new entity in which the exocrine pancreas shows lymphocytic infiltration. There are two subtypes of AIP; Type 1 related with Immunoglobulin G4 (IgG4) as the pancreatic manifestation of IgG4-related disease (IgG4-RD), and Type 2 related with granulocytic infiltration. The characteristic features of Type 1 AIP are increased serum IgG4 levels, lymphoplasmacytic sclerosing pancreatitis (infiltration of IgG4+ plasmacytes and...

ea0056p697 | Clinical case reports - Pituitary/Adrenal | ECE2018

Pasireotide a new option for acromegaly

Haydardedeoglu Filiz Eksi , Bakiner Okan , Bozkirli Emre , Bagir Gulay Simsek , Ertorer Melek Eda

Background: Acromegaly is a rare neuroendocrine disorder caused by secretion of excessive levels of growth hormone. Somatostatin receptor ligands (SRLs) are first-line medical therapies for patients in whom surgery has failed or is contraindicated. We report a case who had inadequate response to multiple therapies including surgery,radiotherapy,octreotide,lanreotide,cabergoline and pegvisomant.Case: An 44-year-old woman was admitted to our hospital with ...

ea0056p1129 | Thyroid cancer | ECE2018

Hounsfield unit value has null effect on thyroid nodules at 18F-FDG PET/CT scans

Haydardedeoglu Filiz Eksi , Bagir Gulay Simsek , Torun Nese , Kocer Nazim Emrah , Reyhan Mehmet , Ertorer Melek Eda

Objectives: Detection rate of thyroid nodules is increasing with use of new imaging modalities, like 18F-fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT). To avoid unnecessary operations, differentiating between benign and malignant 18F-FDG PET/CT-positive thyroid nodules is essential. Many authorities recommend fine needle aspiration biopsy (FNAB) for exclusion of malignancy in thyroid nodules. Although FNAB is a simple, easily performed proc...

ea0070aep173 | Bone and Calcium | ECE2020

Quality of life, depressin and anxiety in patients with hypoparathyroidism

Anaforoglu İnan , Sancak Seda , Murat Akbas Emin , Oruk Gonca , Canat Masum , Aydın Kadriye , Alphan Uc Ziynet , Gorar Suheyla , Cavlak Gulhan , Eren Guzin , Yılmaz Merve , Ekiz Bilir Betul , Bozoglan Humeyra , Akbaba Gulhan , Muslum Tuna Mazhar , Akcay Seckin , Tuzun Dilek , Simsek Bagir Gulay , Eksi Haydardedeoglu Filiz , Yorulmaz Goknur

Patients with hypoparathyroidism may have sypmptoms consistent with physical, emotional and cognitive dysfunctions which may cause impaired quality of life (QOL). We included 266 patients (20–79 years; 231 women/35 men) who were being treated for hypoparathyroidism. They were taking conventional therapies for hypoparathyroidism; calcium, active vitamin D and magnesium when needed. We applied Beck Depression Scale, Anxiety Scale and SF-36 QOL scale to the patients. The et...