Searchable abstracts of presentations at key conferences in endocrinology

ea0081ep14 | Adrenal and Cardiovascular Endocrinology | ECE2022

Adrenal sarcomas – Exceptionally rare or more common than thought? Prevalence in adrenalectomy specimens over 12 months period and presenting features.

Azman Nur , Lawrence James , Hayes Matthew , Douglas James , Bujanova Jana

Adrenal/periadrenal sarcomas are very rare entity of adrenal tumours. An epidemiological analysis of primary adrenal cancers found prevalence of adrenal sarcoma of 1.3% compared to adrenocortical carcinoma (ACC) 43.8%, neuroblastoma 39.7%, pheochromocytoma 10.9% and non-Hodgkin’s lymphoma 4.3% (1). In 2021, 26 adrenalectomies in adults were performed in our institution. 12/26 had malignant histology. 9/26 lesions were > 6 cm. 7/9 lesions > 6 cm were malignant (2 a...

ea0081ep42 | Adrenal and Cardiovascular Endocrinology | ECE2022

Giant non-functioning adrenocortical carcinoma – the elephant in the room

Sim Sing Yang , Bujanova Jana , Hayes Matthew , Tilley Charles , Crabb Simon , Arnez Lorena

Adrenocortical carcinoma (ACC) is a rare malignancy with an incidence of 0.7–2.0 cases/million habitants/year, often with a dismal prognosis. Patients present with abdominal symptoms or symptoms of hormone excess. However, 15% are diagnosed incidentally. (1) A 59y male was referred with progressive lethargy, weight loss, dyspepsia and abdominal distension over the past 2 years. He was dismissive of ‘the elephant in the room’ and in denial. He was pushed to seek ...

ea0086p166 | Adrenal and Cardiovascular | SFEBES2022

Review of multidisciplinary perioperative management of functioning and non-functioning adrenal lesions at The University Hospital Southampton NHSFT (UHS)

Bujanova Jana , Bray Diane , Richard W Lockyer C , C Hayes Matthew , Douglas James , Crabb Simon , Chance Thomas , Al-Mrayat Ma'en

Objective: We reviewed perioperative management of patients undergoing adrenal surgery at UHS between 1/12/2020 to 1/6/2022 (19-month period) since formalisation of its regional adrenal MDT.Results: 45 adrenalectomies were performed during this period with all cases being discussed at the adrenal MDT, of which 24 (53%) were referred from peripheral hospitals. Laparoscopic surgery was performed in 35/45 (78%) (median length of stay (LOS): 3d), open in 10/...

ea0090ep39 | Adrenal and Cardiovascular Endocrinology | ECE2023

“Adrenal Giants” Review of adrenal masses ≥ 10 cm detected and treated during a 10- year period at the University Hospital Southampton NHS Foundation Trust, United Kingdom

Galides Chloe , Hayes Matthew , Douglas James , W C Richard , crabb Simon , Chance Thomas , King Alexander , Al-Mrayat Ma'en , Bujanova Jana

Introduction: The aim of this project was to review all adrenal masses ≥ 10 cm managed in our organisation over a 10-year period (2012-2022).Results: 20 adrenal masses ≥10 cm in maximal diameter were identified (range 10-32 cm, average 16.6 cm, 6 above 20 cm and one above 30 cm). Age at presentation was 17-80 y (mean 56.3 y, 50% F). Duration of symptoms: 1 day-18 months, mean 7.5 months with 6 presenting acutely. Follow-up period: 1 month-122...