Searchable abstracts of presentations at key conferences in endocrinology

ea0034p336 | Reproduction | SFEBES2014

Elevation of HRPE773 (ZG16B) expression in amnion at term and in human ectocervical cell lines treated with inflammatory mediators is consistent with a function in innate immunity

Hayhurst Rachel Rachel , Hibbert Nanette , Frew Lorraine , Stock Sarah , Riley Simon , Morley Steven

Introduction: Labour is an inflammatory process involving the innate immune system, premature activation of which, for example by infection, can lead to preterm birth before 37 weeks of gestation with profound pathophysiological consequences for the offspring. The putative antimicrobial protein HRPE773 (ZG16B) expressed in human female reproductive secretory epithelia, has been shown previously to be elevated in human endometrium during the menstrual early secretory phase and ...