Searchable abstracts of presentations at key conferences in endocrinology

ea0037ep851 | Thyroid cancer | ECE2015

Mixed medullary and papillary thyroid carcinoma – a case report

Senol Emel , Temiz Peyker , Erhan Yamac , Hekimsoy Zeliha

Thyroid cancers are divided into two main subgroups according to their embryonic origin: papillary cancer, the most common histologic type, seen in 75–80%, and medullary cancer, seen in 5–10% (sporadic or as a component of multiple endocrine syndrome). Because of the different phenotypic characteristics of these two cancers, it’s unusual for them to present simultaneously. Since 1980, only a few cases of simultaneous papillary and medullary thyroid cancer have b...

ea0022p704 | Obesity | ECE2010

Vitamin D levels in obese patients with and without metabolic syndrome

Karatas Savas , Hekimsoy Zeliha , Dinc Gonul , Onur Ece , Ozmen Bilgin

Vitamin D role is not only associated with mineral metabolism and bone health but also in globally important diseases such as obesity and metabolic syndrome. The aims of this study were to investigate: i) 25(OH) vitamin D levels in obese patients with and without metabolic syndrome and compare these with levels in healthy subjects, ii) the relationship between serum 25(OH) vitamin D levels and metabolic syndrome components such as body mass index, waist circumference, blood pr...

ea0041ep66 | Adrenal cortex (to include Cushing's) | ECE2016

Iatrogenic Cushing’s syndrome due to misuse of topical corticosteroids: a case report

Ali Acar Emre , Senol Emel , Davarci Sena Ece , Erdem Neslihan , Hekimsoy Zeliha

Introduction: Because of their anti-inflammatory effect, topical corticosteroids are widely used in dermatological diseases. Topical use is typically safe, but serious adverse effects induced by systemic absorption are occasionally reported. We report a patient who developed Cushing’s syndrome due to long-term misuse of topical bethametasone and clobetasol.Case Report: A 24-year-old man presented with rapid weight gain and purple strias in multiple ...

ea0037ep339 | Diabetes (pathiophysiology & epitemiology) | ECE2015

Vitamin D level in impaired fasting glucose and impaired glucose tolerance (prediabetic) patients

Gultekin Mehmet , Hekimsoy Zeliha , Oz Derya , Hatiboglu Ogun , Alarslan Pinar , Ozmen Bilgin , Onur Ece , Gozukara Ceyhun

Introduction: Impaired fasting glucose (IFG) is defined as being present in those whose fasting blood glucose level is consistently elevated above normal, but is not high enough to be considered as having diabetes mellitus. Impaired glucose tolerance (IGT) is defined as being present in those whose second hour plasma glucose level is higher than normal, but is not high enough to be considered as having diabetes mellitus. Low serum 25-hydroxyvitamin D levels are associated with...

ea0037ep1048 | Thyroid (non-cancer) | ECE2015

Menstrual disturbances in thyroid dysfunction

Gungor Gokcen , Hekimsoy Zeliha , Oz Derya , Alarslan Pinar , Hatiboglu Ogun , Ozmen Bilgin

Introduction: Thyroid hormones play an important role in achieving and maintaining reproductive functions. Thyroid dysfunction affects the menstrual cycle and often leads to menstrual irregularity. We prospectively investigated untreated female patients presenting to our Endocrinology and Internal Medicine outpatient clinics.Material and methods: All the patients were of reproductive age and were newly diagnosed with thyroid dysfunction. After a detailed...

ea0026p577 | Cardiovascular endocrinology and lipid metabolism | ECE2011

Rhabdomyolysis associated with fenofibrate: a case report

Oz Derya , Hatipoglu Ogun , Alarslan Pinar , Kurt Hafize , Fidan Nuri , Ozmen Bilgin , Hekimsoy Zeliha

Rhabdomyolysis is a characterized by muscle necrosis and release of intracellular muscle constituents into the circulation. Most cases are associated with a predisposing factor such as high dose statin therapy, diabetes, old age, female gender, renal failure or hypothyroidism.An 80-year-old woman presented with severe and generalized muscle pain. Her medical history included hypertension, congestive heart failure, chronic atrial fibrillation and a thy...

ea0022p100 | Bone/Calcium | ECE2010

Vitamin D status among adults in the Aegean region of Turkey

Hekimsoy Zeliha , Dinc Gonul , Kafesciler Sabriye , Onur Ece , Guvenc Yesim , Pala Tumer , Guclu Feyzullah , Ozmen Bilgin

Vitamin D is a lipid-soluble hormone found in certain foods and synthesized from precursors in the skin when exposed to ultraviolet light. Vitamin D plays a critical role in bone metabolism and many cellular and immunological processes; and low levels have been associated with several chronic and infectious diseases. Vitamin D status is assessed by measuring the concentration of serum 25-hydroxy vitamin D (25(OH) D). Vitamin D deficiency is reported to be common worldwide, but...

ea0022p108 | Bone/Calcium | ECE2010

Bone turnover, serum osteoprotegerin and soluble receptor activator of nuclear factor-Kβ ligand levels in patients with hyperthyroidism

Hekimsoy Zeliha , Kafesciler Sabriye , Taneli Fatma , Aras Feray , Ozmen Bilgin , Guclu Feyzullah

Osteoprotogerin (OPG) and the receptor activators of nuclear factor-kβ (RANK) and nuclear factor-kβ ligand (RANKL) play an important role in bone metabolism. RANKL binds to RANK, which is expressed by osteoclasts, whereas OPG acts as its decoy receptor, blocking the RANK–RANKL interaction.The aim of our study was to evaluate bone turnover parameters (serum calcium, phosphorus, alkaline phosphatase, parathormone, osteocalcine, 24-...

ea0020p113 | Thyroid | ECE2009

The changes of the IL-2,IL-4,IL-12, TNF-α and IFN-γ levels with L-thyroxine treatment in patients with Hashimoto's throiditis

Guclu Feyzullah , Ozmen Bilgin , Kirmaz Cengiz , Kafesciler Sabriye , Taneli Fatma , Hekimsoy Zeliha

Background: Hashimoto’s thyroiditis is a chronic autoimmune thyroiditis. It is the most common cause of primary hypothyroidism in adolescent period, via autoimmune thyroid tissue destruction and affecting 2% of the population. In this study we want to investigate the role of the cytokines such as IL-2, IL-12, TNF-α and IFN-γ in the pathogenesis of the disease and the changes of cytokine levels with the L-thyroxine treatment....

ea0020p249 | Bone/Calcium | ECE2009

Bone mineral density, bone turnover, serum osteoprotegerin and soluble receptor activator of nuclear factor kβ ligand levels in patients with differentiated thyroid cancer

Kafesciler Sabriye Ozkaya , Hekimsoy Zeliha , Taneli Fatma , Aras Feray , Ozmen Bilgin , Guclu Feyzullah

Thyroid hormones play an important role in bone metabolism. The potential action of prolonged levothyroxine therapy on bone mass reduction is stil a matter of debate.The aim of our one year prospective study was to elucidate whether longterm suppressive thyroid hormone therapy in patient with differentiated thyroid cancer (DTC) affects bone metabolism, osteoprotegerin (OPG) and soluble receptor activator of nuclear factor kβ ligand (sRANK-L) and is ...