ea0011p229 | Cytokines and growth factors | ECE2006
Mukherjee A
, Helbert M
, Davis JRE
, Shalet SM
Although prolactin is well recognised as a cytokine, effects of hypoprolactinaemia on biological endpoints are not well described in humans. In-vitro and clinical studies suggest an influence on humoral and cell mediated immunity and autoimmunity. We studied basal and stimulated immune function in panhypopituitary adults with and without prolactin deficiency and age and gender matched healthy controls. The study was approved by hospital and local research ethics committees. Ni...