Endocrine Abstracts

Background: In patients with type 1 diabetes (T1D), arterial stiffness is a potential alternative biomarker for cardiovascular (CV) risk as it has recently shown important prognostic value in the development of CVD that is independent from traditional risk factors. Glycemic control by means of HbA1c is a main determinant of arterial stiffness progression, however the relationship with continuous glucose monitoring (CGM)-derived parameters such as time in range (TIR) has not be...

Background and aims: HbA1c as a gold-standard measure for glycaemic control has been criticized for several years: lacking the ability to capture hypoglycaemia, time spent in different glucose ranges or to reflect glycaemic variability (GV) are frequently reported shortcomings. Continuous glucose monitoring (CGM) can overcome this, and several new CGM-derived parameters have been proposed to provide additional insights, with the concept of time in range (TIR) and other paramet...