ea0063gp84 | Thyroid Nodules and Cancer | ECE2019
Brigante Giulia
, Lazzaretti Clara
, Paradiso Elia
, Foersti Asta
, Hemminki Kari
, Elisei Rossella
, Romei Cristina
, Simoni Manuela
, Landi Stefano
, Casarini Livio
Introduction and aim: Thyroid cancer is the most common endocrine neoplasia affecting 0.21.5% of the individuals worldwide and its incidence is increasing [1]. Papillary thyroid carcinoma (PTC) is the main histotype (8090%). PTC susceptibility is the result of genetic predisposition, environmental factors and lifestyle. We hypothesized that genetic predisposition to PTC is poligenic and characterized by a genetic signature involving combinations of genes previously...