Searchable abstracts of presentations at key conferences in endocrinology

ea0020p276 | Clinical case reports and clinical reports | ECE2009

Possible effects of IGF-1 and IGF-3 in the development of growth failure, type 2 diabetes mellitus and severe insulin resistance in a case of Seckel syndrome

Kebapci Nur , Onbasi Kevser , Yorulmaz Goknur , Efe Belgin , Basmak Hikmet

Seckel syndrome (SS) is described as the prototype of the primordial bird-headed type of dwarfism (Seckel 1960). It represents a spectrum of multisystem abnormalities. We present a case of SS and discuss the possible effects of IGF-1 and IGF-3 in the development of growth failure, type 2 Diabetes Mellitus (DM) and severe insulin resistance (IR).Case: A 21-year-old female was referred to our clinic because of growth retardation and amenorrhea. At birth, s...

ea0020p319 | Clinical case reports and clinical reports | ECE2009

Dwarfism and female extenal genitalia due to congenital partial hypopituitarism in a 46XY Seckel syndrome with microcephaly and multiple skeletal deformities

Kebapci Nur , Efe Belgin , Yakut Ayten , Adapinar Baki , Basmak Hikmet

Seckel syndrome (SS) is a rare disorder of severe growth retardation and craniofacial-skeletal abnormalities. In scant number of reports, neonates had intact hypothalamic┬ľpituitary┬ľadrenal axis before they die because of cardiopulmonary abnormalities. We present an unique case of SS at the age of 18 years and discuss the possible explanations of his growth retardation and sex reversal.Case: A 18-year-old female presented with short stature and ...