ea0028oc1.3 | Young Endocrinologists prize session | SFEBES2012
Gogakos Apostolos
, Hoeg Antonia
, Murphy Elaine
, Mueller Sandra
, Reid David
, Gluer Claus
, Felsenberg Dieter
, Roux Christian
, Eastell Richard
, Koehrle Josef
, Schomburg Lutz
, Williams Graham
T3-action is regulated by three iodothyronine deiodinases, which contain selenium in the active site. It is proposed that Se availability regulates thyroid function. OPUS is a European population-based prospective cohort study of post-menopausal women in which we showed thyroid function within the upper normal range is associated with reduced bone mineral density (BMD) and increased non-vertebral fracture risk. Using strict exclusion criteria we defined reference ranges for th...