ea0037gp.18.02 | Pituitary–Basic and IGF-1 | ECE2015
Vankova Marketa
, Vejrazkova Daniela
, Lukasova Petra
, Bradnova Olga
, Vacinova Gabriela
, Dvorakova Katerina
, Hill Martin
, Vcelak Josef
, Rusina Robert
, Holmerova Iva
, Bendlova Bela
Background and aims: Neuroactive steroids and their metabolites play an important regulatory role in the nervous system affecting the neuronal plasticity, stress response, learning, and memory. The aim of the study was to compare the steroid metabolome in AD patients and controls.Materials and methods: The study comprised of 48 AD patients (30 women and 18 men; age 73.8±9.54 years) and 33 matched controls (22 women and 11 men; age 68.2±5.94 yea...