ea0086p121 | Reproductive Endocrinology | SFEBES2022
, Hopkins Thomas
, Agwuegbo Uche
, Bousfield George
, Jonas Kim
G protein-coupled receptors are the largest family of mammalian receptors, with key roles in controlling most physiological processes. Ovarian function is no exception, with a key ovarian GPCR, follicle stimulation hormone receptor (FSHR), and its endogenous ligand, FSH, critical for pre-antral-antral follicle growth and survival. An increasingly important way that GPCRs have been shown to regulate ligand specificity and signal amplitude is via association and formation of dim...