Searchable abstracts of presentations at key conferences in endocrinology

ea0063p648 | Interdisciplinary Endocrinology 1 | ECE2019

Ghrelin expression in breast carcinomas

Armasu Ioana , Ciobanu Delia-Gabriela , Ianole Victor , Vasiliu Ioana , Hristov Ioana , Leustean Letita , Lupascu Cristian , Mocanu Veronica , Serban Ionela Lacramioara , Preda Cristina

Introduction: Breast cancer is, by far, the most frequent cancer among women. Local and systemic factors have been shown to drive growth in breast cancer cells. There is increasing evidence that hormone ghrelin, known for the growth hormone releasing effect and food intake modulator, may also influence cancer growth. Ghrelin has been shown to be produced by some tumor cells, including breast cancer cells.Objective: To analyze ghrelin expression in correl...

ea0067o27 | Oral Presentations | EYES2019

Subcutaneous white adipocytes histological evaluation in obese bariatric patients: size matters

Hristov Ioana , Timofte Daniel , Hristov Andrei , Tiron Adrian , Tiron Crina , Oboroceanu Teodor , Mocanu Veronica

Introduction: White adipose tissue celularity is a highly versatile and precocious marker for metabolic status. Fat morphology can be estimated by comparing body fat mass with average fat cell size. Recent studies have shown that adipo-cyte hypertrophy is negatively correlated with dyslipidemia and insulin resistance, independent of body composition.Methods: The study group includes 18 obese patients, with a mean age of 38.76±8.89 years and a mean B...

ea0041ep790 | Obesity | ECE2016

Micronutrients status in bariatric patients-middle term follow-up for Sleeve Gastrectomy

Hristov Ioana , Mocanu Veronica , Labusca Luminita , Zugun-Eloae Florin , Ciobanu Delia , Timofte Daniel

Introduction: Sleeve gastrectomy is a highly effective bariatric technique for morbidly obese patients thus nutritional deficiencies resulting need routine screening for proper evaluation.Aim: Little is still known about the nutritional side-effects for this restrictive bariatric procedure and our study aims to evaluate the impact of sleeve gastrectomy on micronutrients status.Methods: Our prospective study included 48 morbidly obe...

ea0032p631 | Growth hormome IGF axis – basic | ECE2013

GH therapy in Turner syndrome: growth rate indirectly correlated with age of therapy initiation

Hristov Ioana , Elena Axinte Ramona , Preda Cristina , Christina Ungureanu Maria , Mogos Voichita

Introduction: Short stature is the most common physical abnormality in Turner syndrome (TS), with adult stature averaging 20 cm shorter compared to the general population.Aim: To study the efficiency of early initiation for GH therapy on final stature for patients with Turner syndrome and to prove it’s important role in obtaining optimal growth rates.Methods: We studied a lot of 24 patients with TS diagnosed and followed up in...

ea0056p537 | Obesity | ECE2018

Differences in adipocyte size and adipogenic potential in metabolically healthy and unhealthy obese bariatric surgery patients

Hristov Ioana , Tiron Crina , Tiron Adrian , Timofte Daniel , Labusca Luminita , Leustean Letitia , Oboroceanu Teodor , Mocanu Veronica

Introduction: The adipocyte expansion is a critical process with implications in the pathogenesis of metabolic syndrome and insulin resistance associated to obesity. Impaired adipogenesis leads to dysfunctional, hypertrophic adipocytes, chronic low grade inflammation and insulin resistance.Methods: Our study included 18 obese patients (13 females and 5 males) mean age 38.76±8.89 years and mean body mass index 46.06±6.48 kg/m2, referred for Lapa...

ea0037ep1218 | Clinical Cases–Pituitary/Adrenal | ECE2015

Rare aetiology for primary adrenal failure: ACTH resistance

Hristov Ioana , Gherasim Simona , Hreniuc Ana , Ungureanu Maria Christina , Preda Cristina , Vulpoi Carmen , Mogos Voichita , Leustean Letitia

Introduction: ACTH resistance syndromes are rare, autosomal and genetically heterogeneous diseases that include familial glucocorticoid deficiency and triple A syndrome. These are characterised by early onset of primary adrenocortical insufficiency associated with hypoglycaemia, convulsions and skin pigmentation.Case report: We present the case of primary adrenal failure in a boy diagnosed at the age of four, during a decompensation episode with hypoglyc...

ea0035p246 | Clinical case reports Pituitary/Adrenal | ECE2014

Prepubertal male gynecomastia-issues of diagnosis

Hreniuc Ana , Gherasim Simona , Hristov Ioana , Preda Cristina , Vulpoi Carmen , Ungureanu Maria-Christina , Cristea Cristina , Mogos Voichita , Leustean Letitia

We present the case of 13 years old boy referred to our service in June 2013 for bilateral gynecomastia (appeared for ~1 year). The boy’s father presented delayed puberty (at 18-year-old). No other pathological hereditary conditions were reported.Clinical examination revealed: gynoid status with height =167 cm (−1.4 DS), weight=63.5 kg, important bilateral gynecomastia with hypo pigmented areola and painful palpation. Sexual development was PI...