Searchable abstracts of presentations at key conferences in endocrinology

ea0049ep1104 | Female Reproduction | ECE2017

Serum concentrations of betatrophin and its association with indirect indices of insulin resistance and beta cell function in women with polycystic ovary syndrome

Adamska Agnieszka , Lebkowska Agnieszka , Jacewicz Malgorzata , Krentowska Anna , Hryniewicka Justyna , Wolczynski Slawomir , Gorska Maria , Kowalska Irina

The accumulated data underline the role of betatrophin in glucose homeostasis. Polycystic ovary syndrome (PCOS) is characterized by insulin resistance and high risk of developing prediabetes and diabetes. The aim of our study was to investigate the relationship of serum betatrophin concentrations with indirect indices of insulin resistance and insulin secretion in women with PCOS, comparing to the control group. The study group comprised 43 women with PCOS and 16 controls matc...

ea0041gp183 | Reproduction & Endocrine Disruption | ECE2016

Intima media thickness and brachial artery flow mediated dilatation in women with polycystic ovary syndrome and type 1 diabetes mellitus

Lebkowska Agnieszka , Adamska Agnieszka , Tolwinska Joanna , Jacewicz Malgorzata , Hryniewicka Justyna , Milewski Robert , Wolczynski Slawomir , Bossowski Artur , Gorska Maria , Kowalska Irina

Polycystic ovary syndrome (PCOS) and type 1 diabetes (T1DM) are accompanied by increased risk of atherosclerosis. A higher prevalence of PCOS in T1DM patients has been reported. Brachial artery flow-mediated dilatation (FMD) and intima media thickness of common carotid artery (IMT) are used to detect an early endothelial dysfunction.The aim of our study was to examine IMT and FMD in T1DM women with PCOS. We also estimated the relation of IMT and FMD to c...

ea0037gp.26.02 | Thyroid – hypothyroidism | ECE2015

High serum IgG4 concentrations in patients with Hashimoto's thyroiditis

Poplawska-Kita Anna , Kosciuszko-Zdrodowska Maria , Siewko Katarzyna , Telejko Beata , Hryniewicka Justyna , Milewski Robert , Szelachowska Malgorzata , Gorska Maria

Purpose: Recent reports strongly suggest that at least some cases of Hashimoto’s thyroiditis (HT) may be closely associated with IgG4-related disease. In the present study we aimed to find out, whether the measurement of serum IgG4 allows for an identification of distinct types of HT, with different clinical, sonographic and serologic characteristics.Methods: The group studied consisted of 53 patients with HT and 28 healthy individuals. All the part...

ea0035p978 | Thyroid (non-cancer) | ECE2014

Body mass analysis in patients with Hashimoto thyroiditis

Poplawska-Kita Anna , Siewko Katarzyna , Telejko Beata , Kosciuszko-Zdrodowska Maria , Hryniewicka Justyna , Szelachowska Malgorzata , Milewski Robert , Gorska Maria

Introduction: Thyroid hormones deficiency in the course of subclinical and overt hypothyroidism is frequently related to the increased body mass, reduced thermogenesis and metabolic rate however the pathogenesis of improper body mass in Hashimoto thyroiditis (HT) patients is still an open question. Therefore, in the present study we compared body mass and body composition between the patients with Hashimoto thyroiditis who were in clinical and hormonal euthyreosis and healthy ...

ea0070aep831 | Reproductive and Developmental Endocrinology | ECE2020

The association of serum miR-27a and miR-320 level with glucose metabolism and insulin sensitivity in young women with polycystic ovary syndrome

Krentowska Anna , Ponikwicka-Tyszko Donata , Lebkowska Agnieszka , Adamska Agnieszka , Sokolowska Gabriela , Sztachelska Maria , Hryniewicka Justyna , Wolczynski Slawomir , Kowalska Irina

Introduction: Polycystic ovary syndrome (PCOS) is associated with an increased risk of insulin resistance. The involvement of microRNAs, small, non-coding molecules, in regulation of metabolic processes has been investigated. The role of miR-27a and miR-320 in regulation of glucose metabolism is documented. The aim of the study was to assess the level of circulating miR-27a and miR-320 in PCOS patients and to investigate its relationship with glucose metabolism.<p class="a...

ea0070ep376 | Reproductive and Developmental Endocrinology | ECE2020

Thyroid peroxidase antibodies in women with polycystic ovary syndrome and type 1 diabetes

Lebkowska Agnieszka , Adamska Agnieszka , Krentowska Anna , Uruska Aleksandra , Rogowicz-Frontczak Anita , Araszkiewicz Aleksandra , Hryniewicka Justyna , Leśniewska Monika , Ożegowska Katarzyna , Wender-Ożegowska Ewa , Zozulinska-Ziolkiewicz Dorota , Kowalska Irina

Objective: Polycystic ovary syndrome (PCOS) is more prevalent among women with type 1 diabetes (T1DM) than in general population. Autoimmune thyroiditis (AIT) is the most common autoimmunological disease in young women in reproductive age, especially in T1DM. Data in literature indicate the possible role of thyroid autoimmunity in PCOS pathogenesis. It has been suggested that positive concentration of thyroid peroxidase antibodies (TPOAbs) is associated with increased prevalen...