Searchable abstracts of presentations at key conferences in endocrinology

ea0017p9 | (1) | BSPED2008

Opportunistic growth measurement in children attending hospital is undertaken infrequently

Lek N , Hughes IA

Background: The UK has advocated a policy of screening childrenÂ’s growth opportunistically. Such a policy has merit if measurements are performed and the data easily retrieved to enable a possible referral for specialist assessment.Height measuredWeight measured N...

ea0017p22 | (1) | BSPED2008

Use of aromatase inhibitor in a boy with short stature and advanced bone age

Thankamony A , Dattani MT , Acerini CL , Hughes IA

Aromatase inhibitors (AIs) have been proposed as a modality in the treatment of short stature in boys. Improvement in final height and predicted final height has been observed in children with constitutional delay of growth and puberty and idiopathic short stature. AIs block the conversion of androgens to estrogens and thus may delay epiphyseal fusion and thereby prolong linear growth. We report our experience with the use of letrozole, a third generation AI, in a boy with gen...

ea0012p32 | Clinical case reports/Governance | SFE2006

Problems in the diagnosis of disorders of sex development

Honour JW , Stanhope R , Hughes IA , Phillips I

A girl with family history of a disorder of sex development (DSD) was referred for biochemical investigations and genetic analysis. Parents were consanguineous and a sibling was thought to have partial androgen insensitivity although androgen receptor gene analysis does not fully explain the phenotype. A maternal uncle with perineal hypospadias and a maternal aunt also had the mutation. One sister was normal, one brother had dextrocardia and another brother had mental retardat...