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Endocrine Abstracts

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ea0059oc3.1 | Obesity & diabetes | SFEBES2018

Kisspeptin stimulates insulin secretion and modulates serum metabolites in humans

Izzi Engbeaya Chioma , Comninos Alexander N , Clarke Sophie A , Jomard Anne , Yang Lisa , Jones Sophie , Abbara Ali , Narayanaswamy Shakunthala , Chia Eng Pei , Papadopoulou Deborah , Prague Julia K , Bech Paul , Godsland Ian F , Bassett Paul , Sands Caroline , Camuzeaux Stephane , Gomez Romero Maria , Pearce Jake TM , Lewis Matthew R , Holmes Elaine , Nicholson Jeremy , Tan Tricia , Ratnasabapathy Risheka , Hu Ming , Carrat Gaelle , Piemonti Lorenzo , Bugliani Marco , Marchetti Piero , Johnson Paul R , Hughes Stephen J , James Shapiro AM , Rutter Guy A , Dhillo Waljit S

Background: Limited data exists on the hormonal mediators connecting metabolism and reproduction. Animal studies show that the reproductive hormone, kisspeptin, may also be important in metabolism. We investigated the effects of kisspeptin on human metabolism for the first time, to explore possible kisspeptin-mediated links between reproduction and metabolism.Methods: We performed intravenous glucose tolerance tests (IVGTTs) in 15 healthy men (age 25&#17...
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Published by BioScientifica

Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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