Searchable abstracts of presentations at key conferences in endocrinology

ea0011p79 | Clinical case reports | ECE2006

Ophthalmic presentations of Cushing’s syndrome

Ibrahim IM , Al-Bermani A , James RA

Introduction: Central Serous Retinopathy (CSR) is a condition characterized by the accumulation of sub-retinal fluid at the posterior pole of the fundus, creating a circumscribed area of serous retinal detachment. It is associated with increased levels of endogenous or exogenous glucocorticoids and has been described in patients with Cushing’s syndrome (CS).Here we report on two cases we recently managed in our unit, with central serous retinopathy ...

ea0011p526 | Endocrine tumours and neoplasia | ECE2006

Estrone and cortisol co-secreting adrenocortical carcinoma in a man presenting with hypogonadotrophic hypogonadism and painful gynaecomastia

Lim EL , Razvi S , Vaikkakara S , Ibrahim IM , Turner S , Johnson S , Mason JI , Lennard TJW , Bliss R , Elloitt S , Richardson D , Neely RD , Quinton R

Case report: A 56-year old man presented with a 3 month history of painful bilateral gynaecomastia and sexual dysfunction. Investigations revealed hypogonadotrophic hypogonadism with markedly elevated serum E2, but otherwise normal baseline anterior pituitary function. Tumour markers were negative and adrenal androgens and LFTs were normal. Imaging identified a ∼6 cm right adrenal mass. Preoperative workup excluded phaechromocytoma, but identified low-grade, ACTH-indepen...

ea0011p85 | Clinical case reports | ECE2006

Langerhans cell histiocytosis: management dilemma for the adult endocrinologist!

Ibrahim IM , Lim E-L , Razvi S , Pearce SHS , Leach N , Quinton R , Mitra D , Wilsdon J , Baborie A , Johnson S , Burt AD , Wood K , Jones G , Windebank K , Pritchard J , Record CO , Bennett SMM

Clinical case: 24-year-old student nurse referred to the liver unit with a 6-month history of pyrexia, cognitive dysfunction and abnormal liver function tests. ERCP was normal; CT scan suggested multiple liver deposits; histology showed both fatty infiltration and focal cholangitis. Medical history included type 1 diabetes since age 7yrs; an unusual skin rash that spontaneously remitted 4 years previously; recurrent vulval ulceration, variously ascribed to candida and/or excor...