Searchable abstracts of presentations at key conferences in endocrinology

ea0032p1052 | Thyroid (non-cancer) | ECE2013

Serum concentrations of cholesterol and triglyceride in patients with type 2 diabetes and incident hypothyroidism

Diez Juan J , Iglesias Pedro

Background: Subclinical thyroid hypofunction and elevation of serum lipid concentrations are two factors that may act synergistically in the increase of cardiovascular risk in patients with type 2 diabetes. However, the association between subclinical hypothyroidism and dyslipidemia is a matter of debate.Objective: Our aim has been to assess whether incident hypothyroidism detected in a screening program is accompanied by elevations in the serum concentr...

ea0081ep144 | Calcium and Bone | ECE2022

Serum calcium, magnesium and phosphorus levels in patients with coronavirus disease 2019: an analysis of their relationship with poor outcome and mortality

Diez Juan Jose , Iglesias Pedro , Garcia Agustin , Casasempere Ignacio Martin , Bernabeu-Andreu Francisco A

Purpose: To assess the impact of serum corrected calcium (CorrCa), magnesium (Mg) and phosphorus (P) levels at hospital admission on SARS-CoV-2 infection outcome.Methods: In this retrospective study, all adult patients with laboratory-confirmed COVID-19 hospitalized in Hospital Universitario Puerta de Hierro Madadahonda during 2020 were included. Demographic, clinical and laboratory data were registered and related to the prognosis of the disease. Poor o...

ea0063p225 | Pituitary and Neuroendocrinology 1 | ECE2019

Efficacy and safety of multimodal therapy in the management of aggresive prolactinoma

Iglesias Pedro , Acitores Alberto , Berrocal Victor Rodriguez , Pian Hector , Navarro Teresa , Alonso Teresa , Diez Juan Jose

Background: Aggressive prolactinomas are rare neoplasms that are characterized by rapid growth and usually large tumor size, invasion of adjacent structures, an aggressive clinical behavior with little response to conventional treatment, high rate of recurrence, and elevated morbidity and mortality.Case Report: 48-year-old woman diagnosed with life-threatening aggressive prolactinoma was referred to us for evaluation of complementary therapy after therap...

ea0063p258 | Pituitary and Neuroendocrinology 1 | ECE2019

Anterior pituitary insufficiency in clinically non-functioning pituitary microadenoma

Arcano Karina , Trivino Vanesa , Garcia-Sancho Paula , Diez Juan Jose , Cordido Fernando , Villabona Carles , Iglesias Pedro

Background: Systematic exploration for anterior pituitary deficiency in patients harboring pituitary microadenomas is not well defined. So far, little is known on the involvement of pituitary function in clinically non-functioning pituitary microadenomas (CNFPM).Objective: To evaluate the prevalence of anterior pituitary insufficiency, defined as at least one hormonal deficiency, in patients diagnosed of CNFPM.Patients and methods:...

ea0049ep784 | Endocrine tumours and neoplasia | ECE2017

Multidisciplinary committee on endocrine tumors: an analysis of 6-year experience

Diez Juan J , Iglesias Pedro , Alonso-Gordoa Teresa , Grande Enrique , Gajate Pablo

Aim: Multidisciplinary approach is mandatory in the management of endocrine tumors. Herein, we summarize the healthcare activity performed during the last 6 years at the multidisciplinary committee for endocrine tumors of a tertiary and University Hospital.Methods: A search of clinical-care activity of the endocrine tumors committee of our hospital from 2011 to 2016 was performed. Clinical and demographic data of all patients were recorded. The committee...

ea0049ep891 | Neuroendocrinology | ECE2017

Clinical features and natural history of clinically non-functioning pituitary incidentalomas

Iglesias Pedro , Arcano Karina , Trivino Vanessa , Garcia-Sancho Paula , Diez Juan Jose , Cordido Fernando , Villabona Carles

Objetive: To assess the clinical features of incidental clinically non-functioning pituitary adenoma (NFPA) and to analyze its natural history.Methods: A multicenter retrospective study in patients with NFPA followed-up from 1992 to 2015 was performed.Results: Fifty-seven patients were studied (29 women (50.9%); age 55.8±16.7 years. 43.9% were older than 60 years, 40.3% belonged to the age group of 40–60 years and 15.8% w...

ea0041ep734 | Neuroendocrinology | ECE2016

Serum concentrations of glucose, cholesterol and triglyceride in men with prolactinoma treated with cabergoline

Dawid Maria del rocio , Arcano Karina , Diez Juan Jose , Villabona Carles , Bernal Carmen , Iglesias Pedro

Introduction: Hyperprolactinemia has been associated with several metabolic abnormalities both in glucose homeostasis, insulin sensitivity, and in lipid profile. Moreover, it has also been reported that many of them seem to improve after normalizing serum prolactin (PRL) concentrations.Objective: To study serum glucose, cholesterol and triglyceride in men with prolactinoma before and after chronic treatment with cabergoline.Patient...

ea0041ep750 | Neuroendocrinology | ECE2016

Nonfunctioning pituitary adenoma: a clinical and pathological study

Arcano Karina , Trivino Vanessa , Garcia Paula , Diez Juan Jose , Cordido Fernando , Villabona Carles , Iglesias Pedro

Objective: To assess clinical outcome after pituitary surgery in patients nonfunctioning pituitary adenomas (NFPA) surgically treated in the past 3 decades in three tertiary referral hospitals.Methods: A multicenter retrospective study on clinical and pathological characteristics, treatment patterns, and outcome in patients with NFPA periodically followed up in specialized neuroendocrinology units who underwent surgery in the period 1982–2015 was pe...

ea0035p874 | Pituitary Clinical (<emphasis role="italic">Generously supported by IPSEN</emphasis>) | ECE2014

Acromegaly and schizophrenia: an incidental association?

Arcano Karina , Dawid Rocio , Diez Juan Jose , Bernal Carmen , Iglesias Pedro

Context: Acromegaly associated to schizophrenia was firstly reported ~60 years ago and, so far it is unclear whether this association is causal or not.Objective: We report on three new cases and discuss the potential pathophysiological mechanisms of this association.Results: We report two males and one female diagnosed with schizophrenia and treated for several years with antipsychotics who developed acromegaly due to a GH-secretin...

ea0056p111 | Endocrine tumours and neoplasia | ECE2018

Effect of 177Lu-dotatate on severe, life-threatening, and refractory hypoglycemia associated with malignant insulinoma

Iglesias Pedro , Martinez Alberto , Gajate Pablo , Alonso Teresa , Navarro Teresa , Diez Juan Jose

Malignant insulinoma is an extremely uncommon tumor (5–10% of insulinomas). It is accompanied by severe hypoglycemia and a short life expectancy (survival at 10 years <10%). Its clinical management is complex and constitutes a real therapeutic challenge. So far, the experience of radionuclide treatment in these tumors is scarce. We report the case of a 51-year-old woman diagnosed with pancreatic neuroendocrine tumor (pNET) in January 2013. Pre-surgical imaging study b...