Endocrine Abstracts

Background: Adults with GH deficiency (GHD) may have an increased risk of cardiovascular disease. Several studies showed that also GHD children may present cardiovascular risk factors. However results are controversial.Objective: Aim of this prospective, case-control study on a large cohort of children with GHD was to evaluate the effects of GHD and GH therapy on cardiovascular risk factors, such as lipid profile, clinical measures of visceral adiposity ...

Background: Patients with classical congenital adrenal hyperplasia (CAH) require life-long therapy with glucocorticoids in order to suppress the androgen production through the inhibition of CRH and consequently ACTH. The therapy must be balanced to avoid either iatrogen hypercortisolism or hyperandrogenism both potentially associated with adverse cardiovascular risk profile.Objective: Aim of this cross-sectional controlled study was to investigate the m...