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Endocrine Abstracts

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ea0099p224 | Adrenal and Cardiovascular Endocrinology | ECE2024

Comparison of antihypertensive effects between eplerenone and esaxerenone, mineralocorticoid receptor antagonists, in patients with primary aldosteronism

Morimoto Satoshi , Takebe Saya , Oyake Kentaro , Kitayama Saori , Ikemoto Makiko , Inoue Yuko , Sano Hisashi , Hirata Kiyotaka , Takano Noriyoshi , Yamashita Kaoru , Seki Yasufumi , Bokuda Kanako , Watanabe Daisuke , Ichihara Atsuhiro

Objective: The efficacy of mineralocorticoid receptor (MR) antagonists has been demonstrated in MR-related hypertension, including primary aldosteronism (PA). Non-inferiority in 24-hour blood pressure reduction has been shown for esaxerenone 2.5 mg/day compared to eplerenone 50 mg/day in patients with essential hypertension. However, no trial has compared the antihypertensive effects of these drugs in patients with PA. This study aimed to investigate the effect of switching fr...

Published by BioScientifica

Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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