Searchable abstracts of presentations at key conferences in endocrinology

ea0022p213 | Clinical case reports and clinical practice | ECE2010

The role of octreotide in the management of young patients with acromegaly

Florescu Alexandru , Grozavu Ilinka , Lisnic Natalia , Apostu Luminita , Moisii Liliana , Poeata Ion , Galesanu Corina

The last decade has provided major progress in the development of highly specific and selective pharmacological agents that have facilitated a more aggressive approach to the treatment of patients with acromegaly. Initial transsphenoidal surgery still appears to be the first line of treatment, but in many cases the biochemical cure targets are not reached and the patient needs adjuvant therapy. Somatostatin analogues have become the mainstay of the medical treatment of acromeg...

ea0020p525 | Paediatric Endocrinology | ECE2009

LEOPARD syndrome and pilocytic astrocytoma: a random association?

Vulpoi Carmen , Rusu Cristina , Zenker Martin , Poeata Ion , Constantinescu Aurora , Indrei Anca , Stoica Ioana , Zbranca Eusebie

Leopard syndrome (LS) is a rare autosomal dominant disease of variable penetrance and clinical expression. LEOPARD is an acronym for the major features of the disorder: lentigines, ECG conduction abnormalities, Ocular hypertelorism, pulmonary stenosis, abnormal genitalia, retardation of growth, and deafness. LS is caused by different mutations in PTPN11 gene (protein-tyrosine phosphatase, nonreceptor-type, 11), allelic with Noonan syndrome (NS). The diagnosis is established if...

ea0035p41 | Adrenal cortex | ECE2014

Periodic cushing's disease: difficult patient, difficult management

Vasiliu Ioana , Scripcariu Viorel , Poeata Ion , Bodescu Ioana , Idriceanu Jeanina , Manolachie Adina , Fadur Alina Daniela , Cristea Cristina , Mogos Voichita , Vulpoi Carmen

Cyclic Cushing’s syndrome is a rare, probably under-reported disorder, characterized by repeated episodes of cortisol excess interspersed by periods of normal cortisol secretion, due to both ACTH-dependent and independent causes, and should be discerned from mild or subclinical Cushing’s syndrome and pseudo-Cushing’s states.We present a female patient 52 years old, with cyclic hypercortisolism clinically manifested and biologically confirm...