Endocrine Abstracts

Kearns-Sayre syndrome (KSS) is a mitochondrial disorder characterized by progressive external ophthalmoplegia, pigmentary retinopathy, together with cardiac conduction defects, muscle abnormalities and endocrinopathies such as growth hormone deficiency (GHD), diabetes and hypoparathyroidism.We present a 2 years 9 months-old boy with clinical and biochemical diagnosis of KSS and GHD. He was referred with failure-to-thrive. He was born at term from healthy...

Introduction: Since bariatric surgery is considered to be a more effective treatment modality for morbid obesity, a growing number of patients have been referred to endocrinology clinics in order to exclude an underlying cause. Routine preoperative testing to screen Cushing’s syndrome (CS) or hypothyroidism is still debatable. The aim of this study is to evaluate the accuracy of routine testing in preoperative endocrinological evaluation.Methods/des...

Introduction: Diabetes mellitus (DM) has been associated with abnormalities of cardiac function and left ventricular hypertrophy. Diabetic individuals, particularly women, had higher heart rates, greater left ventricular wall thicknesses, greater cardiac mass than unaffected subjects. We aimed to investigate association between waist circumference–body mass index (BMI) and left ventricle mass (LVM)-left ventricle mass index (LVMI), left ventricle myocardial perfusion inde...

Aim: The ankle-brachial index (ABI) shows the existence of peripheral arterial disease and is also related to cardiovascular mortality in diabetic patients, even in those with coronary artery disease at an early stage. Normal levels are considered to be an ABI of 0.9 – 1.3; ABI thresholds of less than 0.9 and more than 1.3 are highly suspicious for PAD and high CV risk in diabetic patients. In this study, we planned to investigate the ankle-brachial index values in diabet...

Autoimmune Polyendocrine Syndrome type-1 (APS-1) is a rare monogenic disease (1:100 000 frequency), caused by mutations in the autoimmune regulator (AIRE) gene, which plays a crucial role in the thymus for negative selection of self-reacting T cells. With tissue damage caused by self-reactive immune cells from early stages of life and gradually presenting with symptoms in following years, APS-1 is clinically diagnosed by presence of minimum two components of the classical tria...

Aim: We aimed to evaluate wrist and ankle measurements in patients with and without diabetes-related macrovascular disease.Material and method: 151 consecutive patients with type 2 diabetes who came to our diabetic outpatient clinic were included. We have divided the patients into two groups. Group 1 (patients with diabetes related macrovascular complications) and group 2 (patients without diabetes related macrovascular complications). Group 1 (n</em...

Background: Adrenal venous sampling (AVS) is the gold standard diagnostic approach for differentiating unilateral from bilateral primary aldosteronism (PA). However, it is a costly, invasive, and operator-dependent procedure with restricted availability.Objectives: It was aimed to develop a prediction model based on a simple clinical score with prominent parameters from the current literature for the subtype diagnosis of PA. The contribution of adrenal v...