Searchable abstracts of presentations at key conferences in endocrinology

ea0032p66 | Adrenal Medulla | ECE2013

Plasma free metanephrine and normetanephrine in chronic kidney disease patients

Niculescu Dan , Ismail Gener , Poiana Catalina

Chronic kidney disease (CKD), with or without dialysis, often prompt biochemical tests for pheochromocytoma diagnosis due to high blood pressure, hemodynamic instability or association with certain genetic syndromes. Our objective was to assess plasma free metanephrine and normetanephrine in CKD disease patients, with or without dialysis.Methods: Plasma free metanephrine and normetanephrine were measured by an enzyme-linked immunosorbent assay in 42 pati...

ea0049ep1094 | Endocrine tumours and neoplasia | ECE2017

Study of CYP17 and PSA G158A polymorphisms in prostate cancer

Vladoiu Suzana , Manda Dana , Oros Sabina , Schipor Sorina , Preda Adrian , Gener Ismail , Picu Catalina , Rosca Roxana , Badiu Corin

The relationship between the level of genetic variation in CYP17, PSA genes and prostate cancer has been extensively studied but the results are still unclear. A 450c17a (CYP17) polymorphism A1/A2 was described to be significantly associated to prostate cancer. A SNP in the promotor PSA gene is an A to G substitution at position −158 (G158A) was proposed to interact differently with AR, thereby modifying the expression pattern and occurrence of prostate cancer.<p cla...