Searchable abstracts of presentations at key conferences in endocrinology

ea0033p77 | (1) | BSPED2013

Urinary gonadotrophins: role in assessment and management of disorders of puberty

Lucaccioni Laura , McNeilly Jane D , Mason Avril , Shaikh M Guftar , Giacomozzi Claudio , Iughetti Lorenzo , Ahmed S Faisal

Introduction: With improvements in assays and the increasing need for non-invasive, out-patient based investigations, there is a renewed interest in the use of urinary gonadotrophins (UG) for assessing pubertal progress. This study aims to establish the correlation between serum and urinary LH and FSH in patients undergoing investigation or management of pubertal disorders.Methods/design: Retrospective evaluation of eight patients undergoing investigatio...

ea0039oc6.5 | Oral Communications 6 | BSPED2015

The measurement of urinary gonadotrophins for assessment and management of pubertal disorders

Lucaccioni Laura , McNeilly Jane , McMillan Martin , Kyriakou Andreas , Wong S C , Predieri Barbara , Iughetti Lorenzo , Shaikh M Guftar , Mason Avril , Ahmed S Faisal

Objective: Prospective evaluation of the relationship between first morning urinary gonadotrophins (uGn) measured by immunoassay and corrected for creatinine (uLH:uCr and uFSH:uCr), and basal serum gonadotropins (sLH and sFSH) and in response to LHRH stimulation test. Prospective evaluation of uGn trend in patients receiving GnRH analogue (GnRH-a; decapeptyl SR, 11.25 mg, every 10–12 weeks).Methods: Enrolled 15 (12M) patients evaluated for delayed p...

ea0035p853 | Pituitary Clinical (<emphasis role="italic">Generously supported by IPSEN</emphasis>) | ECE2014

Assessment of the hypothalamus–pituitary–adrenal axis with different corticotropin tests in adult patients with Prader–Willi syndrome

Grugni Graziano , Corrias Andrea , Sartorio Alessandro , Beccaria Luciano , Bocchini Sarah , Di Candia Stefania , Fintini Danilo , Iughetti Lorenzo , Mussa Alessandro , Ragusa Letizia , Gargantini Luigi , Salvatoni Alessandro , Delvecchio Maurizio , Chiumello Giuseppe , Crino Antonino

Introduction: Hypothalamic–pituitary anomalies are well proven in Prader–Willi syndrome (PWS). In this context, it has been previously reported that central adrenal insufficiency (CAI) may be part of the PWS phenotype. However, the diagnostics of CAI is critical and debated, due to the lack of fully reliable tests. Several studies have looked at the clinical usefulness of the low dose (1 μg) short Synacthen test (LDSST) compared to the conventional dose (250 &#9...