Searchable abstracts of presentations at key conferences in endocrinology

ea0011p131 | Clinical case reports | ECE2006

Seeking an appropriate sex of rearing in 5 α-reductase deficiency

Iyer S , Thomas RM , Cheetham T

5 α-reductase deficiency is a rare autosomal recessive condition of male psuedohermaphroditism, resulting from mutations of the type 2 isoenzyme 5 α-reductase, crucial in conversion of testosterone to dihydrotestosteroneCase report: Baby P is a full term baby, a product of a consanguineous marriage. The baby had ambigous genitalia with a clitoris, minimal glans tissue at the apex of the labial folds, gonads in the labioscrotal folds and a ureth...

ea0017p50 | (1) | BSPED2008

Influence of body mass index and inherited insulin sensitivity on the age of diagnosis and autoantibody status in childhood Type 1 diabetes

Howey C , O'Sullivan J , Ram R , Iyer S , Leech N , Cheetham T

Introduction: The incidence of Type 1 diabetes (T1D) is rising. The effect of increasing BMI in children has been proposed. A relationship between age of diagnosis of T1D and BMI SDS has been reported by some but not confirmed in all studies. We propose age of diagnosis and autoantibody status may be influenced by BMI and inherited factors relating to BMI and insulin resistance.Methods: BMI SDS was calculated in 230 children with newly diagnosed T1D, 4&#...