ea0011p403 | Diabetes, metabolism and cardiovascular | ECE2006
Nettleship JE
, Jones RD
, Biggins CM
, Channer KS
, Jones TH
Low endogenous testosterone is associated with atherosclerosis in elderly men. The aim of this study was to examine the role of the androgen receptor (AR) in the development of atherosclerosis and determine whether an inactive AR coupled with testosterone deficiency, inherent to the testicular feminised (Tfm) mouse, is associated with atherosclerosis following cholesterol feeding compared to surgically-castrated male littermates with AR intact.Ten-week-o...