Searchable abstracts of presentations at key conferences in endocrinology

ea0032p1071 | Thyroid (non-cancer) | ECE2013

Autoimmune hypo to hyperthyroidism: a rare evolution

Marcelino Mafalda , Silva Joao , Passos Dolores , Jacome de Castro Joao

Introduction: Hashimoto thyroiditis (HT; with anti-thyroid peroxidase antibodies (TPOAb)) and Graves’ disease (GD; with TSH receptor antibodies (TRAbs)) are frequent autoimmune disorders responsible for thyroid dysfunction. There are two types of TRAbs, the ones that stimulate the thyroid (TSAb) causing Graves’ hyperthyroidism and those that block thyrotropin action (TBAb) being occasionally responsible for hypothyroidism. Unusual patients switch from TSAb to TBAb (o...

ea0041ep448 | Diabetes (to include epidemiology, pathophysiology) | ECE2016

Clinical inertia in type 2 diabetes mellitus without insulin treatment

Silva Joao , Ivo Catarina , Lopes Luis , Passos Dolores , Simoes Helder , Marcelino Mafalda , Jacome de Castro Joao

Introduction: Clinical inertia applied to type2 Diabetes Mellitus (T2DM) treatment, is defined as a lack of treatment’s intensification of patients who are not in HbA1c target. Clinical inertia leads to a postponement of new therapeutic introduction, with all complications associated with a poor metabolic control. In Portugal there are only studies that show good or poor metabolic control but do not mention clinician’s attitude towards these values. Recently publishe...

ea0016p305 | Endocrine tumours | ECE2008

A rare case of hiperandrogenism bilateral Leydig cell tumor of the ovary

Marcelino Mafalda , Nobre Ema Lacerda , Conceicao Joao , Carvalho Arlindo , Horta Ana Paula , Jacome de Castro Joao

Background: The androgen-secreting tumors constitute fewer than 1% of ovarian tumors. Leydig cell tumor is one of the most common of this type of lesion and it is usually benign, small and unilateral.Case report: A 67-year-old women was referred to the Endocrine clinic due to hirsutism (score 22 Ferriman–Gallwey) and male type alopecia with 3 years of evolution and progressive worsening. Biochemically she had high levels of serum testosterone –...

ea0063p965 | Diabetes, Obesity and Metabolism 3 | ECE2019

Prediabetes: expectations and attitudes

Ivo Catarina , Duarte Vitoria , Verissimo David , Silva Joao , Lopes Luis , Passos Dolores , Jacome de Castro Joao , Marcelino Mafalda

Introduction: Prediabetes is a very prevalent disease. About 27.4% of Portuguese adults suffer from this condition. Prediabetes is defined as intermediate hyperglycemia state associated with the simultaneous presence of insulin resistance and β-cell dysfunction as diabetes, with increased risk of developing macro and microvascular complications. Approximately 7% of individuals with prediabetes will progress to diabetes per year. This study aims to characterize a populatio...