Searchable abstracts of presentations at key conferences in endocrinology

ea0016p800 | Thyroid | ECE2008

Insulin resistance and oxidative stress induce advanced glycation end products formation in patients with clinical and subclinical hypothyroidism

Peppa Melpomeni , Hadjidakis Dimitrios , Alevizaki Maria , Dimitriadis George , Isari Georgia , Economopoulos Theofanis , Uribarri Jaime , Vlassara Helen , Raptis Sotirios A

Introduction: Advanced glycation end products (AGEs) formation is accelerated in various pathological conditions characterized by insulin resistance (IR) and/or increased oxidative stress (OS). Hypothyroidism – overt (OH) or subclinical (SUH) – is associated with a variety of metabolic disorders leading to IR and increased OS.Aim: To estimate the εN-carboxymethyl-lysine (CML) levels, in subjects with OH and SUH and seek f...

ea0037ep624 | Obesity and cardiovascular endocrinology | ECE2015

Levels of advanced glycation end products (AGEs), AGE's receptor (sRAGE) and their relationship with cardiovascular risk factors in newly diagnosed type 2 diabetic patients

Villegas-Rodriguez Etzabel , Solorio-Meza Sergio , Fajardo-Araujo Martha Eugenia , Uribarri Jaime , Malacara Juan Manuel , Torres-Graciano Sofia , Garay-Sevilla Ma Eugenia

Diabetes is associated with a greatly increased risk of cardiovascular disease and the advanced glycation end products (AGEs) and their receptors play an important role in these complications.Objective: To study the association between AGEs and sRAGE levels with cardiovascular risk factors in obese and non-obese newly diagnosed type 2 diabetic patients.Material and methods: We conducted a cross-sectional study in subjects with type...