Searchable abstracts of presentations at key conferences in endocrinology

ea0041gp51 | Cardiovascular endocrinology | ECE2016

Pericardial rather than intramyocardial fat is independently associated with systolic and diastolic left ventricular heart function in metabolically healthy humans

Wolf Peter , Winhofer Yvonne , Smajis Sabina , Jankovic Drazenka , Anderwald Christian-Heinz , Trattnig Siegfried , Luger Anton , Krebs Michael , Krssak Martin

Background: Obesity is a major risk factor to develop heart failure, in part due to possible lipotoxic effects of increased intramyocardial (MYCL) and/or pericardial (PERI) lipid accumulation. Recent evidence suggests that MYCL is highly dynamic and might rather be a surrogate marker for disturbed energy metabolism than the underlying cause of cardiac dysfunction. On the other hand, PERI might contribute directly by mechanic and paracrine effects. Therefore, we hypothesized th...