Searchable abstracts of presentations at key conferences in endocrinology

ea0063p309 | Reproductive Endocrinology 1 | ECE2019

Ano-genital distance in children born of mothers with polycystic ovary syndrome – Odense Child Cohort

Glintborg Dorte , Jensen Richard Christian , Schmedes Anne Vibeke , Brandslund Ivan , Kyhl Henriette Boye , Nielsen Tina Kold , Andersen Marianne Skovsager

Background: Higher testosterone levels during pregnancy in women with polycystic ovary syndrome (PCOS) could be associated with longer offspring ano-genital distance (AGD).Aims: To compare AGD between offspring of mothers with PCOS and controls and to determine possible associations between maternal 3rd trimester testosterone levels and offspring AGD at three months of age.Methods: The study was part of the prospective s...

ea0081oc9.1 | Oral Communications 9: Environmental Endocrinology | ECE2022

Higher free thyroxine associated with pfas exposure in first trimester. The odense child cohort

Jensen Richard Christian , Glintborg Dorte , Timmermann Clara Amalie Gade , Nielsen Flemming , Boye Henriette , Bilenberg Niels , Madsen Jeppe Buur , Grandjean Philippe , Jensen Tina Kold , Andersen Marianne

Background: Perfluoroalkyl substances (PFAS) are endocrine disrupting chemicals, with elimination half-lives ranging from four to eight years. Experimental studies found PFAS able to interfere with thyroid hormone-binding proteins. During the first 20 weeks of gestation (GW), the fetus is reliant on placental transfer of maternal thyroid hormones, mainly free thyroxine (FT4). However, previous studies investigating associations between exposure to PFAS and thyroid hormone stat...

ea0090ep23 | Adrenal and Cardiovascular Endocrinology | ECE2023

REPLACE: Effect of hydrocortisone and placebo in patients with partial adrenal insufficiency after cessation of glucocorticoid treatment; A study protocol for a multi-centre, randomised, double-blinded, placebo-controlled clinical trial

Dreyer Anja Fenger , Borresen Stina Willemoes , Hansen Simon Boggild , Al-Jorani Hajir , Bislev Lise Sofie , Boesen Victor Brun , Christensen Louise Lehmann , Glintborg Dorte , Jensen Richard Christian , Jorgensen Nanna Thurmann , Klose Marianne , Lund Marie Louise , Stankovic Jelena , Tei Randi , Watt Torquil , Feldt-Rasmussen Ulla , Jorgensen Jens Otto , Andersen Marianne

Background: Glucocorticoid (GC) formulations are widely used as anti-inflammatory treatment, and synthetic GC, e.g. prednisolone, is the cornerstone treatment of polymyalgia rheumatic (PMR) and giant cell arteritis (GCA). Long-term pharmacological GC treatment may induce adrenal insufficiency (GIA). Adrenal function is, however, not routinely assessed after discontinuation of long-term GC treatment, and it is unknown, if hydrocortisone replacement is beneficial. This study aim...