Searchable abstracts of presentations at key conferences in endocrinology

ea0020p18 | Adrenal | ECE2009

Bilateral adrenal incidentalomas – a clinical study of 1710 patients observed at a single endocrinological centre

Kasperllik-Zaluska Anna , Slowinska-Srzednicka Jadwiga , Roslonowska Elzbieta , Kochman Magdalena , Zgliczynski Wojciech , Jeske Wojciech , Otto Maciej , Cichocki Andrzej

In the last 18 years 1710 patients with incidentally found adrenal tumours=adrenal incidentalomas (AI), 1300 women (F/M=2.8), aged 10–87 years, were registered at our department. In 338 of them (20%) bilateral tumours were detected. This study aimed at analyzing character of bilateral tumours and defining methods of their management. The size: 1.0–13 cm (in the group of 1710 patients: 1.0–23 cm) most of them up to 3.5 cm. Hormonal and imaging studies were perfor...

ea0014p133 | (1) | ECE2007

Adrenal incidentaloma, an oncological or endocrinological enigma? Clinical analysis of 1300 cases observed at a single endocrinological centre

Kasperlik-Zaluska Anna , Roslonowska Elzbieta , Slowinska-Srzednicka Jadwiga , Zgliczynski Wojciech , Jeske Wojciech , Papierska Lucyna , Otto Maciej , Slapa Rafal , Cichocki Andrzej , Cwikla Jaroslaw

Objective: Incidentally found adrenal tumour (adrenal incidentaloma = AI) is the most frequent adrenal disorder. Every patient with AI has to be evaluated carefully to choose the best method of management. We present our experience with a group of 1300 patients with AI, registered at our department.Material and methods: Material consisted of 1300 patients (female/male ratio 2.6, age 10–87 years) with AI ranging in size from 0.8 to 23.0 cm. Methods: ...

ea0035p176 | Cardiovascular Endocrinology & Lipid Metabolism | ECE2014

Serum and plasma aldosterone levels and the respective aldosterone/plasma renin indices in healthy blood donors

Glinicki Piotr , Jeske Wojciech , Kapuscinska Renata , Zgliczynski Wojciech

Introduction: Primary aldosteronism (PA) is one of the causes of hypertension. Blood aldosterone and the aldosterone/direct renin concentration (DRC) are routinely used as a screening test for PA.Aim of study: Whether it matters if aldosterone concentration is determined in serum or plasma samples?Material and methods: 145 healthy males, five females (blood donors) were investigated. In all subjects blood was collected into two tub...

ea0035p532 | Endocrine tumours and neoplasia | ECE2014

Comparison of chromogranin A levels in serum and plasma (EDTA2K) and the respective reference ranges in healthy males

Glinicki Piotr , Jeske Wojciech , Kapuscinska Renata , Zgliczynski Wojciech

Introduction: Chromogranin A (CgA) is a main, nonspecific marker of neuroendocrine tumours (NET). There are various commercially assays for the measurement of CgA concentration in serum or plasma. These assays differ in analytical techniques (RIA, ELISA, CLIA), have different standardization, and use different antibodies which recognize different epitopes of CgA molecule.Aim of study: Our study was designed to confirm the noted earlier differences in CgA...

ea0035p1070 | Thyroid (non-cancer) | ECE2014

Ultrasound thyroid imaging, TSH and anti-thyroid peroxidase antibodies concentrations in Warsaw adolescents: the influence of family history of thyroid disease: preliminary results

Kochman Magdalena , Gapys Dorota , Kapuscinska Renata , Jeske Wojciech , Wycisk Aleksandra , Zgliczynski Wojciech

Introduction: Data regarding the thyroid gland evaluation in Polish adolescents are limited.Aim: The aim of the study was to asses TSH and anti-thyroid peroxidase antibodies (anti-TPO) concentrations as well as thyroid morphology on ultrasound in Warsaw adolescents in regard of family history of thyroid disease.Materials and methods: The study was carried out on a group of 480 adolescents (285 girls and 195 boys), aged 17–18 y...

ea0022p19 | Adrenal | ECE2010

Adrenal incidentalomas accompanying malignant tumours: clinical study of 1888 patients

Kasperlik-Zaluska Anna A , Slowinska-Srzednicka Jadwiga , Roslonowska Elzbieta , Jeske Wojciech , Cichocki Andrzej , Otto Maciej , Zgliczynski Wojciech

Diagnostic procedures reveal that majority of incidentally found adrenal tumours (adrenal incidentalomas, AI) appear to be benign adenomas. However, AI accompanying malignant tumours must be diagnosed very carefully to take a proper decision concerning their management. In the registry of the Department of Endocrinology in Warsaw, there are 1888 patients (1388 women, 500 men, F/M ratio 2.8) with AI, 10–87 years old. Primary malignant tumours were diagnosed in 155 patients...

ea0014p380 | (1) | ECE2007

Adiponectin in patients with Graves’ ophthalmopathy (GO)

Jastrzebska Helena , Gietka-Czernel Malgorzata , Janik Jadwiga , Czajka-Oraniec Izabella , Jeske Wojciech , Karczmarzyk Regina , Zgliczynski Wojciech

Adiponectin is a soluble protein produced solely by matured adipocytes. Adipogenesis contributes to the pathogenesis of GO in many ways including a direct effect on proptosis due to increased volume of mature adipocytes.The aim of the study was to estimate an influence of immunosupresive and anti-inflammatory treatment using systemic corticotherapy combined with orbital radiotherapy on serum adiponectin level in GO patients. The study was accepted by Eth...

ea0022p12 | Adrenal | ECE2010

Autoimmune disorders in Addison's disease and in isolated secondary adrenal insufficiency

Kasperlik-Zaluska Anna A , Czarnocka Barbara , Jeske Wojciech , Bednarek-Papierska Lucyna , Hulting Anna-Lena , Bensing Sophie , Crock-Ludecke Patricia , Kampe Olle

Autoimmunity is the most frequent cause of Addison’s disease (AD). Isolated secondary adrenal insufficiency (ISAI) in patients not treated with corticosteroids seems to be an autoimmune disease too. In the registry of the Department of Endocrinology in Warsaw we have 328 patients with AD and 305 patients with ISAI. Autoimmune AD was diagnosed in 262 of 328 patients (77%) and in 217 of them (83%) some associated autoimmune disorders were found, while in the group with ISAI...

ea0020p13 | Adrenal | ECE2009

Autoimmune adrenal insufficiency: Addison's disease versus idiopathic isolated secondary adrenal insufficiency

Kasperlik-Zaluska Anna , Czarnocka Barbara , Jeske Wojciech , Papierska Lucyna , Hulting Anna-Lena , Bensing Sophie , Crock Patricia , Kampe Olle

Studies on autoimmune Addison’s disease (AD) have a long tradition, while knowledge on idiopathic isolated secondary adrenal insufficiency (SAI), which also seems to be caused by autoimmunity, is not so popular. Our presentation aimed at comparing two groups of patients: 1) 238 patients with AD (183 women, F/M=4.3), aged 8–61 years at time of diagnosis and 2) 301 patients with SAI (269 women, F/M=8.4), aged 17–87 years at time of diagnosis. Maximum time of durat...

ea0035p557 | Endocrine tumours and neoplasia | ECE2014

Adrenal incidentaloma: is it a disease of elderly? A clinical study of 2650 cases registered at a single endocrinological center

Kasperlik-Zaluska Anna , Otto Maciej , Cichocki Andrzej , Slapa Rafal , Rozkowszka Katarzyna , Slowinska-Srzednicka Janina , Roslonowska Elzbieta , Jeske Wojciech , Zdunowski Piotr , Zgliczynski Wojciech

It is generally believed that frequency of incidentally found adrenal tumours (adrenal incidentaloma(AI)) increases with age. Our study aimed at an analysis of age patterns in our group of patients with AI.Design: Material: 2650 patients, 1943 womens, 707 men. The diagnostic basis: clinical examination, imaging studies, hormonal determinations, pathomorphological and cytochemical investigations of the surgically removed 755 adrenal tumours. The material ...