Searchable abstracts of presentations at key conferences in endocrinology

ea0090ep677 | Pituitary and Neuroendocrinology | ECE2023

Prevalence and clinical characteristics of hyponatremia following pituitary surgery

Kosak Mikulas , Netuka David , Masopust Vaclav , Majovsky Martin , Jiskra Jan , Jezkova Jana

Introduction: Hyponatremia is one of the possible complications of pituitary surgery. Mild, asymptomatic hyponatremia can be managed with fluid restriction and oral supplementation, however more profound hyponatremia, especially when symptomatic, can be a reason for hospital readmission and often needs to be treated with saline infusion in ICU.Aims: To estimate prevalence of hyponatremia and provide clinical characteristics in the cohort of patients who ...

ea0020p574 | Neuroendocrinology, Pituitary and Behaviour | ECE2009

Is it possible to avoid hypopituitarism after the irradiation of pituitary adenomas by the Leksell gamma-knife?

Marek Josef , Jezkova Jana , Hana Vaclav , Krsek Michal , Liscak Roman , Vladyka Vilibald

Radiation therapy is used in the treatment of pituitary adenomas, especially in failures of neurosurgery and pharmacotherapy to reduce the size of adenomas and normalize their hypersecretion. Conventional fractionated radiotherapy has achieved good results, but only after a long latency, with considerable postradiation morbidity and with very frequent appearance of hypopituitarism. The focal stereotactic targeting allowed by Leksell gamma-knife (LGK) was supposed to decrease t...

ea0090p596 | Calcium and Bone | ECE2023

Surgery of primary hyperparathyroidism during pregnancy: case series

Libansky Petr , Fialova Martina , Jezkova Jana , Kosak Mikulas , Matejkova Behanova Magdalena , Moravcova Jitka , Vcelak Josef , Vaculova Marketa , Lischke Robert

Background: Primary hyperparathyroidism can occur at any age, the typical patient is a postmenopausal woman, primary hyperparathyroidsim is found rare by pregnant women. The maternal symptoms are similar to the symptoms by postmenopausal women.Materials and methods: Among the years 2000-2022 we have performed 3459 operations (including 6,6% reoperations) with diagnosis of hyperparathyroidism, there were six women, who underwent parathyroidectomy during p...

ea0016p400 | Neuroendocrinology | ECE2008

Impaired microvascular reactivity and endothelial function in patients with Cushing's syndrome

Durovcova Viktoria , Prazny Martin , Jezkova Jana , Horova Eva , Hana Vaclav , Kvasnicka Jan , Pecen Ladislav , Marek Josef , Skrha Jan , Krsek Michal

It is well known that hypercortisolism is associated with increased morbidity and mortality caused predominantly by vascular and atherosclerotic complications. The effect of hypercortisolism on microvasculature is less known. The aim of this study was to evaluate skin microvascular reactivity (MVR) in relation to arterial hypertension, diabetes mellitus and other possible influencing factors (fibrinolysis, oxidative stress and endothelial function) in patients with Cushing&#14...