Searchable abstracts of presentations at key conferences in endocrinology

ea0081rc11.5 | Rapid Communications 11: Thyroid 2 | ECE2022

Which factors can influence the occurrence of two nondiagnostic results in fine-needle aspiration cytology of the same thyroid nodule?

Cosme Ines , Silvestre Catarina , Joao Bugalho Maria

Introduction: Fine-needle aspiration cytology (FNAC) of thyroid nodules can be associated with non-diagnostic (ND) results, despite the usage of ultrasound (US) guidance. It is recommended to repeat the FNAC because of the possible risk of malignancy in these nodules.Aim: To evaluate the influence of demographic, clinical and echographic characteristics in the recurrence of ND FNAC in a thyroid nodule.Methods: Retrospective review ...

ea0090p710 | Pituitary and Neuroendocrinology | ECE2023

Chordomas of the parasellar region: description of 4 cases of a rare disease

Cosme Ines , Nobre Ema , Joao Bugalho Maria

Background: Chordomas are rare, invasive and slow growing bone tumours with different locations. Parasellar chordomas are even more rare and the initial manifestations include visual and/or neurological symptoms. In addition, endocrine dysfunction may be present. We describe 4 cases of parasellar chordomas.Clinical cases: 1) Female, 55-years-old, reported headache associated with restriction of left eye movement for the past 3 months. Brain magnetic reso...

ea0081p350 | Diabetes, Obesity, Metabolism and Nutrition | ECE2022

Prevalence of autoantibodies in paediatric and adult patients with type 1 diabetes mellitus – study of a Portuguese cohort

Cosme Ines , Silvestre Catarina , Nunes Daniel , Lemos Carlos , Joao Bugalho Maria , Proenca Helena

Introduction: Almost all type 1 diabetes mellitus (T1DM) patients have autoantibodies (ab) at disease onset. These ab prevalence varies according to patientsÂ’ age, origin and disease duration.Aim: Determine diabetes mellitus ab prevalence in a paediatric and adult T1DM Portuguese according to their age on diagnosis, gender and diabetes duration.Methods: Retrospective review of T1DM ab (glutamic acid decarboxylase 65 autoantibo...

ea0049ep329 | Clinical case reports - Thyroid/Others | ECE2017

Autosomal dominant hypocalcemia in a Portuguese family: novel mutation in the calcium-sensing receptor gene

Gomes Vania , Ferreira Florbela , Silvestre Catarina , Castro Raquel , Joao Bugalho Maria

Introduction: Autosomal dominant hypocalcemia (ADH) is a rare condition, caused by activating mutations in the calcium-sensing receptor (CASR) gene. Affected individuals have hypocalcemia with inappropriately low parathyroid hormone (PTH) levels.Case report: A 50-year-old woman, asymptomatic, was referred to our Endocrinology department for investigation of hypocalcemia detected in routine blood analysis (serum corrected calcium was 7.4 mg/dl &#...

ea0049ep1055 | Pituitary - Clinical | ECE2017

Hypogonadotropic hypogonadism in a patient with long-term primary hypothyroidism

Vaz de Castro Raquel , Maria Aragues Jose , Ferreira Florbela , Gomes Vania , Wessling Ana , Joao Bugalho Maria

Abstract: We report the case of a 65-year-old man who presented with erectile dysfunction to an appointment in our Endocrinology department. He referred fatigue, weight gain and constipation as secondary complaints that had been steadily evolving throughout the past 4 years. He denied other symptoms such as visual impairment or headaches as well as the consumption of any medications or drugs. His past medical history was unremarkable. On examination, BMI was 25.8 kg/m2</s...

ea0090p475 | Reproductive and Developmental Endocrinology | ECE2023

Not what it seems: an exuberant case of hirsutism in polycystic ovary syndrome

de Grine Severino Mariana , Vaz Lopes Marta , Peixe Carolina , Vicente Rocha Jose , Lacerda Nobre Ema , Joao Bugalho Maria

Introduction: Hirsutism is the presence of terminal hair growth in females with a male distribution pattern. It affects 5-15% of women, being an important sign of androgen excess. The main causes of hirsutism are polycystic ovary syndrome (PCOS) and idiopathic hyperandrogenism. Other significant but less frequent causes of hirsutism include nonclassic congenital adrenal hyperplasia (NCAH), androgen-secreting tumors, and CushingÂ’s syndrome.Case repor...

ea0090ep1030 | Thyroid | ECE2023

Primary Thyroid Lymphoma: Clinical Course vs High Suvmax in Fdg-Pet

Lopes-Pinto Mariana , Aparicio David , Paula Ricca Lacerda Nobre M Caetano Ema , Dolores Lopez-Presa Maria , Joao Bugalho Maria

Introduction: Primary thyroid lymphomas (PTL) account for 5% of all thyroid malignancies. Treatment and prognosis depend on tumor subtype. Contrasting with diffuse large B-cell lymphomas (DLBCL), that have an aggressive clinical course and higher maximum standardized uptake value (SUVmax) in Fluorine-18-fluorodeoxyglucose positron emission tomography (FDG-PET), thyroid extranodal marginal zone B-cell lymphomas of mucosa-associated lymphoid tissue (MALT) usually show an indolen...

ea0022p413 | Endocrine tumours &amp; neoplasia (<emphasis role="italic">Generously supported by Novartis</emphasis>) | ECE2010

Von Hippel-Lindau disease: a case report

Gouveia Sofia , Ribeiro Cristina , Paiva Sandra , Joao Bugalho Maria , Santos Jacinta , Vieira Alexandra , Alves Marcia , Carvalheiro Manuela

Introduction: Von Hippel-Lindau disease (VHLD) is a rare autosomal-dominant syndrome, characterized by the development of multiple cysts and tumours, namely retinal and central nervous system hemangioblastomas, renal cell carcinoma (RCC), phaeochromocytoma, pancreatic endocrine tumours (PET) and endolymphatic sac tumours.Most germinal mutations are missense, related to a high risk for presenting phaechromocytoma (specially if Arg167Trp mutation im...

ea0056p517 | Diabetes therapy | ECE2018

Long-term results of continuous subcutaneous insulin infusion on glycemic control and severe hypoglycemias

do Vale Sonia , Carvalho Raquel , Matos Tania , Costa Cristiana , Filipa Martins Ana , Silvestre Catarina , Joao Bugalho Maria

Introduction: The use of Continuous Subcutaneous Insulin Infusion (CSII) is expected to improve glycemic control and to reduce hypoglycemia events. However, long-term beneficial results in glucose control are not always observed. We evaluated long-time glucose control and severe hypoglycemias in type 1 diabetic patients using CSII, without continuous glucose monitoring.Patients and methods: This was a retrospective study of adult type 1 diabetic patients...

ea0056ep120 | Pituitary and Neuroendocrinology | ECE2018

Macroprolactinoma found in obesity setting: case report

Sofia Osorio Ana , Filipa Martins Ana , Vieira Joao , Barbosa David , Faria Carolina , Nobre Ema , Joao Bugalho Maria

Obesity is growing fast worldwide. Although environmental factors play a major role, endocrine dysfunction may contribute to the weight gain. We report an invasive macroprolactinoma diagnosed in obesity setting. A 35-year-old male was referred to our endocrine outpatient department due to grade 2 obesity (IMC 38.4 Kg/m2). His weight was increasing since the beginning of his professional activity at the age of 20 due to a sedentary lifestyle. On physical examination he had an h...