Searchable abstracts of presentations at key conferences in endocrinology

ea0014oc4.2 | Neuroendocriology basis | ECE2007

Growth Hormone-Releasing Hormone (GHRH) exerts protective effects on adult rat hippocampal progenitor cells

Destefanis Silvia , Johansson Inger , Aberg David , Granata Riccarda , Ghigo Ezio , Isgaard Jorgen

Growth hormone releasing hormone (GHRH) is a neuropeptide mainly synthesised in the hypothalamus, known to exert a stimulatory effect on the synthesis and release of growth hormone (GH) from the pituitary via the activation of specific receptors. New data indicate that GHRH is also produced in both extrahypothalamic brain areas and in peripheral tissues. GHRH-receptor splice variants (SVs) have been found in several peripheral normal and neoplastic human tissues and mediate ef...