Searchable abstracts of presentations at key conferences in endocrinology

ea0012p21 | Clinical case reports/Governance | SFE2006

An illustration of the potent anti-natriuretic effect of growth hormone

Misra S , Drake WM , Johnston LB

The anti-natriuretic properties of growth hormone (GH) are well established. GH deficiency (GHD) results in salt and water depletion and studies confirm that replacement leads to sodium and vasopressin-mediated water retention, in patients with intact posterior pituitary function.We report the case of a 20-year-old male patient with septo-optic dysplasia, fixed cranial diabetes insipidus (DI) and an abnormal thirst threshold. He first presented after bir...

ea0013s66 | Dealing with MEN | SFEBES2007

Dealing with MEN: A paediatric perspective

Martin Lee , Chan Li , Savage MO , Johnston LB

Multiple endocrine neoplasia type 2 (MEN2) is an autosomal dominant condition that is rare in childhood. MEN2 is sub-classified into three categories that all include familial medullary thyroid carcinoma (MTC). Familial MTC has no other associated tumours. MEN2A is characterised by MTC, phaeochromocytoma and parathyroid tumours and MEN2B consists of MTC, phaeochromocytoma, ganglioneuromatosis and usually a Marfanoid habitus. The identification of RET as the causative gene has ...