Endocrine Abstracts

Introduction: Children and young people (CYP) are increasingly being screened and identified with early-stage type 1 diabetes (T1D). Benefits of an earlier T1D diagnosis include a reduction in diabetic ketoacidosis, hospitalisation and a ‘softer landing’ into insulin therapy. Early-stage T1D is defined by having ≥2 islet autoantibodies (IAb), categorised into stage 1 (normoglycaemia), stage 2 (dysglycaemia), and stage 3 (hyperglycaemia). CYP with a single IAb a...

Introduction: Iodine is essential for thyroid hormones synthesis, and fetal/infant neurodevelopment. There is increasing evidence of iodine insufficiency among British women. The MABY study is a longitudinal cohort study assessing the iodine and thyroid status of pregnant women and their offspring.Methods: Healthy women were recruited (target 697 mother/infant pairs) from antenatal clinics at gestational week (GW) 28±1. Blood and urine were collecte...

Background: General population screening for type 1 diabetes (T1D) using islet autoantibodies (IAb) is gaining international momentum, since screening reduces diabetic ketoacidosis, hospitalisation and identifies individuals eligible for future preventative treatments. Qualitative studies have only been undertaken in at-risk individuals (1). We therefore aimed to explore parents’ experiences of their child taking part in a general population T1D screening...