Searchable abstracts of presentations at key conferences in endocrinology

ea0014p146 | (1) | ECE2007

Time necessary to achieve the maximum effect of goserelin, LH-RH agonist, in therapy of hormone dependent breast cancer

Murgic Jure , Matovinovic Martina , Fabijanic Lucija , Katalinic Darko , Vrkljan Milan

Nearly one third of women diagnosed with invasive breast cancer are younger than 50 years with regular menstrual cycles. 60% of these tumors express estrogene and progesterone receptors. Common treatment procedure is surgery followed by chemotherapy, radiotherapy and hormone therapy. Often in younger patients chemotherapy causes permanent amenorrhoea. In case that menses afterwards occurs ovarial suppression is needed, mostly by goserelin, LH-RH agonist. The principle of thera...

ea0014p6 | (1) | ECE2007

Evaluation of neuroendocrine disfunction in hypothalamo-pituitary-adrenal axis in diagnosis of depressive and non-depressive alcohol-dependent persons

Matovinovic Martina , Katalinic Darko , Maric Andreja , Solter Miljenko , Ivica Josip , Resetic Josip , Murgic Jure , Vrkljan Milan

Acute and chronic alcohol intake and alcohol withdrawal induce dysfunction of neuroendocrine and other regulatory systems. The aims of this study were to assess a possible hypothalamo-pituitary-adrenal (HPA) axis dysfunction in population of alcoholics, using dexamethasone suppression test (DST). The study was approved by local Ethical Committee. The serum and urinary cortisol were compared between the groups of 89 male patients (64.5% depressive and 35.5% nondepressive alcoho...

ea0014p349 | (1) | ECE2007

Thyroid hormones in serum and cerebrospinal fluid in patients with brain tumor and acute stroke

Katalinic Darko , Matovinovic Martina , Solter Miljenko , Maric Andreja , Murgic Jure , Vrkljan Milan , Dobrovic Karolina

We studied levels of T3, T4, FT3, FT4, rT3 and TSH concentrations in serum and FT3, FT4, rT3 and TSH concentrations in cerebrospinal fluid (CSF) in 10 patients with brain tumor and 20 patients with acute stroke and compared them to 7 patients in control group (further clinical evaluation in control group did not show brain lesions). All patients were euthyroid. The study was approved by loc...