Searchable abstracts of presentations at key conferences in endocrinology

ea0069oc7 | Oral Communications | SFENCC2020

Management challenges in a patient with papillary thyroid carcinoma and resistance to thyroid hormone

Yajnik Parag , Kahal Hassan , Talbot Fleur

Resistance to thyroid hormone (THR) is a rare genetic condition affecting the nuclear thyroid hormone receptor, and inherited in a dominant negative pattern. It is often diagnosed in patients with discordant thyroid function. Patients have a ‘pituitary resistance’ to the elevated circulating levels of thyroid hormone, resulting in the failure of TSH suppression. While this consequent TSH drive has been associated with follicular thyroid cancer, it is thought that coe...

ea0028p365 | Thyroid | SFEBES2012

Secondary hypothyroidism with silent thyroiditis - A Case Report

Pothina Narayana Prasad , Kahal Hassan , Wakil Ammar

Introduction: Central hypothyroidism is frequently seen after pituitary surgery, radiation therapy or head injury. We present a case of silent thyroiditis in a patient with secondary hypothyroidism. Case Description A 24 year old woman complained of tiredness during her periodic review in the endocrine clinic. Her endocrine history included surgery for craniopharyngioma at the age of 3 years and subsequent hypopituitarism with growth hormone, ACTH deficiency, diabetes insipidu...

ea0022p220 | Clinical case reports and clinical practice | ECE2010

Primary ovarian carcinoid presenting as right heart failure – case report

Pothina Narayana Prasad , Kahal Hassan , Malik Mohamed

Introduction: Carcinoid tumours commonly originate from the gastrointestinal tract. Cardiac manifestations occur in 10–41% of patients with carcinoid syndrome, usually associated with liver metastases. We report an atypical case of a carcinoid tumour associated with right sided heart disease without distant metastases.Case description: A 75-year-old lady with no significant past medical history and a lifelong non-smoker, was admitted with 3 months h...

ea0044ep44 | (1) | SFEBES2016

A case of reversible elevation in liver enzymes in a patient with poorly controlled type 1 diabetes

Obisi Nneka , Al-Hakim Adam , Kahal Hassan , Allan Belinda

Introduction: Hyperglycaemia induced elevation in alanine aminotransferase (ALT) in people with type 1 diabetes has been well described in children but is a less recognised complication in adults.CaseAn 18 year old slim girl was admitted to hospital with diabetic ketoacidosis (DKA). She had type 1 diabetes for 16 years and recurrent hospital admissions with DKA. Her HbA1C was 126 mmol/mol. After correction of her DKA and restarting...

ea0038p490 | Thyroid | SFEBES2015

Preoperative parathyroid imaging: a retrospective audit

Winfield Natalie , Kahal Hassan , Jayagopal Vijay , Agada Frank

Introduction: Preoperative ultrasonography or Sestamibi scanning (or both) of the parathyroid glands could facilitate a focused or minimally invasive surgical approach. In this audit, we wanted to find out whether one form of imaging is superior to the other in correctly identifying a parathyroid adenoma, later confirmed on histology.Methods: Data were collected from consecutive patients who underwent parathyroidectomy for primary hyperparathyroidism, co...

ea0022p186 | Clinical case reports and clinical practice | ECE2010

Pseudophaeochromocytoma: case series of a common cause

Kahal Hassan , Pothina Narayana Prasad , Tahrani Abd , Malik Mohamed

Introduction: Phaeochromocytomas commonly present with episodes of sweating, palpitations, and hypertension. Urinary catecholamines measurement is the most common screening test for suspected phaeochromocytoma in the UK. We report a series of three cases in which the reason for hypertension and raised catecholamines was not a phaeochromocytoma and treating the underlying condition corrected the clinical and biochemical abnormality.Cases: Three patients w...

ea0044p185 | Obesity and Metabolism | SFEBES2016

A retrospective study assessing the effects of OSA in women with PCOS attending the weight management clinic

Kahal Hassan , Dimitriadis George K. , Kyrou Ioannis , Ali Asad , Tahrani Abd A , Randeva Harpal

Introduction: Obstructive Sleep Apnoea (OSA) is more common in women with Polycystic Ovary Syndrome (PCOS). There is paucity of data regarding the impact of OSA in women with PCOS.Methods: We conducted a retrospective study using electronic patients’ records of premenopausal women with PCOS who were first seen in the weight management clinic (WMC) between March/2008 and November/2014. PCOS diagnosis was documented either by referring clinician or es...

ea0028p127 | Clinical practice/governance and case reports | SFEBES2012

A case of normocalcaemic hyperparathyroidism

Konya Judit , Kahal Hassan , Wakil Ammar , Sathyapalan Thozhukat , Atkin Stephen , Aye Mo

Introduction: Normocalcemic hyperparathyroidism is a less recognised variation of primary hyperparathyroidism (pHPT). Patients present with normal calcium and elevated level of PTH.Case: A 70 years old woman presented to her general practitioner with left sided loin pain. She had no past medical history of note and she was not taking any medications. Ultrasound of the urinary tract showed bilateral nephrocalcinosis. Her blood tests showed raised PTH leve...

ea0028p192 | Obesity, diabetes, metabolism and cardiovascular | SFEBES2012

The role of metabolic dyslipidaemia in screening for impaired glucose regulation in polycystic ovary syndrome

Aye Myint M , Kahal Hassan , Smith H , Sandeman D , Kilpatrick Eric , Atkin S

Background: Women with polycystic ovary syndrome (PCOS) are commonly associated with insulin resistance, metabolic syndrome and a family history of diabetes mellitus (DM). They are therefore at risk of diabetes and dyslipidaemia. Diabetes UK (2006) recommends screening for diabetes in PCOS patients who have a body mass index (BMI) ≥30. The recommended test is fasting plasma glucose (FPG). We therefore investigated 55 PCOS patients and 33 healthy volunteers to test the hy...

ea0025p326 | Thyroid | SFEBES2011

The effect of parathyroidectomy on neuropsychological symptoms in patients with asymptomatic primary hyperparathyroidism

Kahal Hassan , Aye Mo , Rigby Alan , Sathyapalan Thozhukat , England James , Atkin Stephen

Introduction: With increased biochemical screening primary hyperparathyroidism (pHPT) is discovered incidentally while patients are still asymptomatic.Objective: To assess the impact of surgery on neuropsychological symptoms in people with apparent asymptomatic pHPT.Methods: Twenty-four patients with asymptomatic pHPT requiring parathyroidectomy, in accordance with NIH recommendations, were recruited prospectively between May 2005 ...