Endocrine Abstracts

Hyperleptinemia is associated with such risk factors for cardiovascular disease as insulin resistance, obesity and hypertension. Recently, it has been identified that leptin has prothrombotic properties and increases the accumulation of oxidant radicals in endothelial cells. It is hypothesized that leptin may be also one of the mediators promoting atherosclerosis.The objectives of the work were to:determine whether there are any co...

Polycystic ovary syndrome (PCOS) is the most common endocrinopathy in women of reproductive age and is characterized by hyperandrogenism and menstrual disturbances. It is known that insulin resistance is associated with polycystic ovary syndrome and with obesity.The objective of this study was to assess the prevalence of glucose intolerance and diabetes in women with PCOS and to examine the role of body mass index in the development of this complications...