Searchable abstracts of presentations at key conferences in endocrinology

ea0032p237 | Clinical case reports – Pituitary/Adrenal | ECE2013

Suppurative meningitis as a life threatening primary presentation of macroprolactinomas

Akkache Lina , Daffeur Katia , Kalafate Nadia , Haddad Meriem , Chentli Farida

Introduction: Suppurative meningitis (SM) is a life threatening disease. It is rarely observed as a primary presentation in large pituitary tumours (PT) destroying the sellar floor and/or invading the skull base. Our aim is to report 3 SM revealing macroprolactinomas.Case No. 1: A man aged 22, consulted for vomiting and fever. The diagnosis of SM was confirmed by lumbar puncture and blood cultures. Cerebral MRI showed multidirectional PT invading caverno...

ea0032p571 | Endocrine tumours and neoplasia | ECE2013

Visceral and tumour abormalities in subjects with acromegaly

Haddad Meriem , Daffeur Katia , Akkache Lina , Kalafate Nadia , Chentli Farida

Introduction: Acromegaly is a relatively rare disease with numerous complications. Our aim is to look for visceral abnormalities and tumour development in subjects with GH and insuIin like GH (or IGF1) excess.Subjets and methods: It is a retro-and prospective study that takes in account 112 patients at diagnosis, with pur pituitary tumours secreting GH, or mixed tumours secreting prolactin and GH diagnosed between 1980 and 2012. They all were questioned ...

ea0032p945 | Pituitary – Clinical (<emphasis role="italic">Generously supported by IPSEN</emphasis>) | ECE2013

Hemiparesis and hemiplegia as clinical presentation in subjects with pituitary tumours

Haddad Meriem , Daffeur Katia , Kalafate Nadia , Akkache Lina , Chentli Farida

Introduction: Generously supported by IPSEN)-->Pituitary tumours are known to cause headaches and visual troubles by compressing pituitary adjacent structures. Pressure on more distant structures is exceptional. In very large tumours such as prolactinomas, mixed adenomas or craniopharyngiomas, hydrocephalus, convulsions, memory troubles and even unconsciousness can be observed, but to our best knowledge motor deficits, such as hemipl...

ea0031p261 | Pituitary | SFEBES2013

Ophtalmological, endocrine, and neurological complications in giant male prolactinomas.

Chentli Farida , Daffeur Katia , Akkache Lina , Haddad Meriem , kalafate Nadia

Introduction: Prolactinomas are more invasive in males. Giant ones (height ≥4 cm) are relatively rare in literature.Our aim is to analyze their frequency, their radiological aspects, and their neurological, endocrine and ophthalmological complications.Methods: All of them had clinical exam, hormonal, ophthalmological, and radiological assessment based on cerebral MRI. Mixed adenomas were excluded. Positive diagnosis was based...

ea0032p212 | Cardiovascular Endocrinology &amp; Lipid Metabolism | ECE2013

Metabolic disorders in a group of Algerian hypersomatotropic subjects

Chentli Farida , Haddad Meriem , Daffeur Katia , Saraoui Fatima , Kalafate Nadia , Akkache Lina , Meskine Djamila

Introduction: Glucose metabolism disorders are well known in subjects with GH excess, but little is known about other metabolic abnormalities. Our aim is to analyze metabolic complications in subjects with acromegaly and pituitary gigantism.Subjects and methods: Records of 111 subjects were retrospectively examined, mean GH=62 ng/ml (n<5), mean age=39.11 (14–60). All had routine analysis for fasting blood glucose, cholesterol, triglycer...

ea0032p957 | Pituitary – Clinical (<emphasis role="italic">Generously supported by IPSEN</emphasis>) | ECE2013

Somatotrop adenomas: comparison between men and women in algerian population

Daffeur Katia , Haddad Meriem , Saraoui Fatima , Akkache Lina , Kalafate Nadia , Meskine Djamila , Chentli Farida

Introduction: Pituitary adenomas in general are deemed to be more aggressive in males. Our aim is to analyze somatotrop adenomas (SA) characteristics and neurological complications. In the second time we will compare male and female cases.Subjects and methods: In this retro-and prospective study, 112 pure and mixed SA diagnosed between 1980 and 2012 were analyzed. They all had hormonal assessment (GH before and after OGTT±IGF1, PRL, cortisol, ACTH, ...

ea0032p958 | Pituitary – Clinical (<emphasis role="italic">Generously supported by IPSEN</emphasis>) | ECE2013

Non functionning pituitary adenomas

Kalafate Nadia , Daffeur Katia , Safer Amel , Haddad Meriem , Akkache Lina , Chentli Farida

Introduction: Non functioning pituitary adenomas (NFPA) frequency varies from 15 to 30% among all pituitary adenomas. Some authors think they are more aggressive and at risk of pituitary apoplexy. Our aim is to analyze their characters and their complications.Subjects and methods: It is a retrospective study that takes in account 37 subjects having a NFPA and recruited from 2005 to 2012. Among this group only 13 have been operated on and had immunochemic...