Searchable abstracts of presentations at key conferences in endocrinology

ea0063ep120 | Pituitary and Neuroendocrinology | ECE2019

Management challenge of child hood Cushing disease

Adel Meriem , Jemel Manel , Kandara Hajer , Kalthoum Mahdi , Nagi Sonia , Kammoun Ines

Introduction: CushingÂ’s syndrome (CS) is rare in children. The most common cause of CS in children is exogenous or iatrogenic CS. The most common cause of endogenous CS is Cushing disease (CD). Pediatric CD is almost always caused by a pituitary microadenoma. Here we present a rare case of (CD) related to pituitary macroadenoma.Clinical observation: An 11 year old boy presented with complaints of excessive appetite and progressive weight gain. He ha...

ea0056p1025 | Thyroid (non-cancer) | ECE2018

Rare association of primary hyperparathyroidism and toxic multinodular goiter

Elfekih Hamza , Elleuch Mouna , Ghorbel Dorra , Hadjkacem Faten , Ammar Mouna , Kalthoum Mahdi , Charfi Nadia , Abid Mohamed

Introduction: The association of primary hyperparathyroidism (PHPT) and hyperthyroidism secondary to toxic multinodular goiter (TMNG) is rarely described in the literature. Hereby, we describe the clinical, biological, and radiological characteristics of two patients having this rare association.Observations: First case: A 66 years-old female was diagnosed with primary hyperthyroidism. Her thyroid antibodies were negatives. During the follow-up, she pres...

ea0063ep60 | Diabetes, Obesity and Metabolism | ECE2019

Kidney failure without proteinuria in a population of diabetic women: can we incriminate diabetes?

Jemai Chaima , Hajer Kandara , Mahdi Kalthoum Med , Maram Mosbeh , Emna Feleh , Hana Belhadj , Manel Jemel , Ines Kammoun

Introduction: The pathophysiology of diabetic nephropathy is characterized by proteinuria which often precedes the decline in creatinine clearance. The objective of our study was to describe the clinical and metabolic characteristics of a population of diabetic femele patients with renal failure without proteinuria.Methods: This is a retrospective study that included 37 diabetic women who had been hospitalized at the National Institute of Nutrition of Tu...

ea0049ep189 | Endocrine tumours and neoplasia | ECE2017

An unknown giant neuroendocrine tumor

Rekik Nabila , Ghorbel Dorra , Mnif Fatma , Kalthoum Mahdi , Mrabet Houcem , Charfi Nadia , Elfekih Hamza , Mnif Mouna , Abid Mohamed

Introduction: Neuroendocrine tumors may develop in almost any organ. These types of tumors may present with giant and asymptomatic mass. We describe a case of a large non functional neuroendocrine tumor reported in the department of endocrinology and diabetology of Hedi Chaker hospital in Sfax-Tunisia in 2016.Presentation of case: A 28 years old male presented with asthenia, gastric heaviness and epigastric pain. Further computerized tomography, a large ...

ea0049ep770 | Clinical case reports - Thyroid/Others | ECE2017

Myasthenia gravis associated with Graves’ disease and adrenal insufficiency

Elleuch Mouna , Elfekih Hamza , Hadjkacem Faten , Kalthoum Mahdi , Ammar Mouna , Rekik Nabila , Safi Wajdi , Mnif Mouna , Abid Mohamed

Introduction: Multiple autoimmune syndrome (MAS) is a rare condition, first described by Humbert and Dupond in 1988 and characterised by three or more autoimmune disorders in the same individual.Case description: Here we present a case of 14-year-old female patient diagnosed with ocular myasthenia gravis. The diagnosis of GravesÂ’ disease was suspected on the basis of hyperthyroidism symptoms and confirmed by undetectable TSH level (<0.01 mUI/l) ...

ea0049ep1128 | Female Reproduction | ECE2017

Secondary amenorrhea after bone marrow transplantation and adjuvant chemotherapy misdiagnosed as disorder of sex development: a case report

Elleuch Mouna , Ammar Mouna , Kacem Faten Hadj , Ghorbel Dorra , Rekik Nabila , Charfi Nadia , Kalthoum Mahdi , Mnif Mouna , Abid Mohamed

Introduction: Disorders of sex development (DSD) is a congenital condition in which the development of chromosomal, gonadal or genital sex is atypical. A female appearance patient with secondary amenorrhea and 46 XY karyotype seems to be solid evidences to diagnose Y-chromosome-related DSD diseases, while it is not necessarily the accurate diagnosis. We here report a case of a 16- year-old girl with secondary amenorrhea and 46 XY karyotype after bone marrow transplantation (BM...