Endocrine Abstracts

Introduction: Primary thyroid lymphoma (PTL) is a rare cause of malignancy, accounting for <5% of thyroid malignancies and < 2% of extra-nodal lymphomas. Most thyroid lymphomas are non-Hodgkin’s lymphomas of B-cell origin. Patients with Hashimoto’s thyroiditis are at greater risk for developing PTL. Early diagnosis is important as treatment and prognosis of PTL depend upon the histology and stage of the tumour at diagnosis. We report a rare case of primary th...

Introduction: Primary thyroid lymphoma (PTL) is a rare cause of malignancy, accounting for <5% of thyroid malignancies and < 2% of extra-nodal lymphomas. Most thyroid lymphomas are non-Hodgkin’s lymphomas of B-cell origin. Patients with Hashimoto’s thyroiditis are at greater risk for developing PTL. We report a rare case of primary thyroid lymphoma in a patient presenting with a rapidly enlarging thyroid goitre highly suspicious of anaplastic thyroid carcinom...

We present a case of a 26 years old female who was rushed to hospital with 4 days history of abdominal pain, vomiting and dizziness. She also had one episode of diarrhoea. Further history revealed that she had lost 32 kilograms of weight over the last 18 months through diet and exercise. There were no signs suggestive of an eating disorder.On examination she was peripherally cold, tachycardic (117/min), hypotensive (86/50 mmHg) and sweaty. Her Glasgow Co...

Introduction: Primary hyperparathyroidism (PHPT) is the third most common endocrine disorder; its evaluation includes biochemical investigations and imaging studies prior to surgical intervention. Imaging is advised as an aide to surgery and not for diagnostic purposes. Coexistence of PHPT and vitamin D deficiency is common; however, the exact nature of the relationship (causal vs secondary) is not clear.Subject and methods: We conducted a retrospective ...

Introduction: Autoimmune polyendocrine syndrome type 2 is a rare disease characterized by the presence of autoimmune Addison’s disease in combination with thyroid autoimmune disease and/or type 1 diabetes mellitus, and possible occurrence of other autoimmune non-endocrine disorders. The combination of the three glands diseases is even rarer and is referred to as Carpenter’s syndrome.A long time interval is often present between the manifestatio...

Background: Prolactinomas are the major subtype (20–30%) of pituitary adenomas. Microprolactinomas (<1 cm) are commoner in females, whereas macroprolactinomas (>1 cm) occur mainly in men. Giant prolactinomas are rare (2–3% of prolactinomas) – features include size of ≥4 cm, with significant extrasellar extension and prolactin levels of >1000 μg/l.Case report: We report the case of a 35-year-old man with type 2 diabet...

Introduction: Unilateral proptosis may be due to thyroid eye disease (TED) or retro-orbital tumours. TED is an autoimmune process affecting orbital and periorbital tissue, and generally occurs in patients with Graves thyrotoxicosis. A small subset of patients with TED (5%) have normal thyroid function, but TED is rarer in hypothyroid patients.Case report: We report the case of a 57-year-old lady who initially presented to ophthalmology with diplopia. She...