Searchable abstracts of presentations at key conferences in endocrinology

ea0059p041 | Bone and calcium | SFEBES2018

Management of osteogenesis imperfecta in adulthood – a single centre experience

Dar Shujah , Khalily Naveed , Khan Shakib , Kamwa Vicky , Cole Trevor , Ayuk John , Gittoes Neil , Hassan-Smith Zaki

Introduction: Osteogenesis imperfecta (OI) is a genetic, heterogeneous, connective tissue disorder most commonly caused by mutations in type I collagen genes. A hallmark of disease is frequent fractures that are precipitated by minimal trauma. There are limited data on the impact of OI on non-skeletal outcomes across the lifecourse. We present cross-sectional data of one of the largest single centre patient cohorts of OI in adulthood (n=186).The aim of this study was ...