Searchable abstracts of presentations at key conferences in endocrinology

ea0038p464 | Thyroid | SFEBES2015

Timing of food intake and L-thyroxine replacement – a cost saving simple change of phrasing in the British National Formula

Kannan Rajendran Bellan

Background: Despite relevant evidence that the absorption and/or action of L-thyroxine is compromised by various factors including the diet, until 2014 the British National Formula (BNF) recommended that L-thyroxine be taken ‘preferably before breakfast’ only, with no further clarifications. To follow is one of the cases where untimely food intake in hypothyroid patients manifested with severe hypothyroidism due to L-thyro...

ea0034p93 | Clinical practice/governance and case reports | SFEBES2014

Can a random cortisol predict outcome of short Synacthen test in non-acute patients with low pre-test probability?

Kannan Rajendran Bellan , Krishnasamy Senthil , Nayak Ananth , Jose Biju , Varadhan Laks

Background: Short Synacthen test (SST) is being increasingly used in various clinical conditions, mainly for completion purpose of ruling out adrenocortical insufficiency rather than actively suspecting it (for instance hypothyroidism with tiredness, type 1 diabetes with hypoglycaemia). The aim of our retrospective analysis was to assess if a random cortisol could predict the outcome of SST.Method: Data were collected on all SST done at the endocrine uni...

ea0034p123 | Clinical practice/governance and case reports | SFEBES2014

Hypomagnesaemia during proton pump inhibitor therapy causing functional hypoparathyroidism

Krishnasamy Senthilkumar , Abbott Vineet , Kannan Rajendran Bellan , Varughese George , Nayak Ananth , Varadhan Laks , Jose Biju

Proton pump inhibitors (PPI) are widely prescribed. PPI-induced diarrhoea and hypomagnesaemia are well-documented in literature. Hypomagnesaemia is well-known to cause functional hypoparathyroidism. We describe a patient who had transient profound hypoparathyroidism which improved on discontinuing PPI and normalising severe hypomagnesaemia.A 72-year-old male, who was on oral anti-diabetic medications, calcium/vitamin D3 supplements and PPI, presented wit...

ea0034p143 | Clinical practice/governance and case reports | SFEBES2014

Mayer-Rokitansky-Kuster-Hauser syndrome and pituitary adenoma: a co-incidence?

Kannan Rajendran Bellan , Nayak Ananth , Varadhan Laks , Varughese George , Jose Biju

Background: Mullerian agenesis or Mayer-Rokitansky-Kuster-Hauser (MRKH) syndrome is a congenital failure of the Mullerian duct to develop, resulting in complete or partial absence of the cervix, uterus, and vagina. It can be isolated (MRKH type I) or associated with renal, vertebral, and, to a lesser extent, auditory and cardiac defects (MRKH type II). Pituitary disease is not a known association. We report a patient who has isolated MRKH syndrome (MRKH type I) and a pituitary...