Searchable abstracts of presentations at key conferences in endocrinology

ea0073aep90 | Calcium and Bone | ECE2021

Fibrosis 4 score is associated with bone density measures in postmenopausal women

Armeni Eleni , Augoulea Areti , Paschou Stavroula , Palaiologou Anastasia , Kaparos Georgios , Panoulis Konstantinos , Lambrinoudaki Irene

IntroductionThe routine assessment of postmenopausal women involves screening for cardiometabolic risk factors and bone health. Evaluation of the liver function is not commonly performed, even though this could be easily performed with the use of indirect markers, such as the Fibrosis 4 score. Recent evidence supports an association between liver cirrhosis and bone turnover, affecting both the trabecular and the cortical bone. Therefore, we aimed to expl...

ea0073aep97 | Calcium and Bone | ECE2021

Osteoporosis and prevalent vertebral fractures are associated with insulin resistance in non-diabetic postmenopausal women

Armeni Eleni , Augoulea Areti , Paschou Stavroula , Soureti Anastasia , Kaparos Georgios , Rizos Dimitrios , Antoniou Aris , Panoulis Konstantinos , Lambrinoudaki Irene

IntroductionRecent evidence suggests a possible link between prediabetes and lower density in postmenopausal populations. Moreover, earlier data suggest a link between diagnosis of diabetes and lower levels of bone density in women after the menopausal transition. We aimed to evaluate the possible association between insulin resistance and a diagnosis of lumbar or hip osteoporosis and/or prevalent fractures of the lumbar spine. Met...

ea0073aep236 | Diabetes, Obesity, Metabolism and Nutrition | ECE2021

The intensity of menopausal hot flushes is associated with values of the hepatic steatosis index

Armeni Eleni , Augoulea Areti , Paschou Stavroula , Karagkouni Iliana , Mili Nikoletta , Kontou Lorena , Kaparos Georgios , Rizos Dimitrios , Panoskaltsis Theo , Lambrinoudaki Irene

IntroductionMenopausal transition is associated with an increase in the cardiovascular risk, possibly related with the sharp decrease of estrogen levels. Menopausal symptoms and more specifically hot flushes have been previously linked with an increase in cardiovascular risk. On the other hand, non-alcoholic fatty liver disease is considered as another presentation of the metabolic syndrome, conferring additional cardiovascular risk to the affected indiv...

ea0063p140 | Diabetes, Obesity and Metabolism 1 | ECE2019

Predictors of incident hypertension in healthy, non-diabetic postmenopausal women with normal renal function

Stamatelopoulos Kimon , Apostolakis Michael , Augoulea Areti , Paschou Stavroula A , Armeni Eleni , Panoulis Konstantinos , Bakas Panagiotis , Georgiopoulos Georgios , Kaparos George , Rizos Dimitrios , Lambrinoudaki Irene

Introduction: The aim of this study was to investigate the incidence of hypertension and to identify potential risk factors in healthy, non-diabetic recently postmenopausal Greek women with normal renal function.Patients and methods: In this retrospective cohort study, we evaluated 141 recently postmenopausal women at baseline and annually thereafter (follow-up time: 1 to 8 years). Blood samples were obtained and ultrasound evaluations were performed at ...

ea0070aep1003 | Hot topics (including COVID-19) | ECE2020

The NOS3 and CYBA gene polymorphisms are associated with subclinical atherosclerosis and arterial stiffness in premenopausal women

Armeni Eleni , Chatzivasileiou Panagiota , Stergiotis Stefanos , Rizos Demetrios , Kaparos Georgios , Augoulea Areti , Alexandrou Andreas , Georgiopoulos Georgios , Laina Aggeliki , Stamatelopoulos Kimon , Lambrinoudaki Irene

Introduction: Differences in the prevalence and prognosis of cardiovascular disease have been linked with gender specific risk factors as well as the differential impact of sex hormones. Moreover, specific genetic polymorphisms may increase further the risk of cardiovascular disease development. Polymorphisms of genes encoding the NADPH/NADPH oxidase system and the endothelial nitric oxide synthase (eNOS) have been associated with atherosclerosis in the general population, but...

ea0073aep570 | Reproductive and Developmental Endocrinology | ECE2021

Flow medicated dilation is associated with matrix metalloproteinase-2 in healthy postmenopausal women

Armeni Eleni , Georgiopoulos Georgios , Delialis Dimitrios , Augoulea Areti , Paschou Stavroula , Mili Nikoletta , Chondrou Asimina , Kouerinis Efthymios , Chatzivasileiou Panagiota , Kaparos Georgios , Eleftheriadis Makarios , Stamatelopoulos Kimon , Lambrinoudaki Irene

IntroductionMenopausal transition has been associated with an increase in cardiovascular risk, which is possibly linked with the hormonal imbalance following ovarian senescence. Both insulin levels and circulating androgens (FAI) have been associated with endothelial dysfunction, through studies evaluating flow mediated dilation (FMD). We aimed to investigate whether the link between these hormones and FMD might be explained by markers of oxidative stres...