Searchable abstracts of presentations at key conferences in endocrinology

ea0049oc5.5 | Cardiovascular Endocrinology | ECE2017

Sex dimorphism of renal corticosteroid signaling during development and long term consequence on blood pressure

Dumeige Laurence , Storey Caroline , Decourtye Lyvianne , Nehlich Melanie , Lhadj Christophe , Viengchareun Say , Kappeler Laurent , Lombes Marc , Martinerie Laetitia

Sex differences have been demonstrated in various biological processes such as arterial blood pressure. However, the potential sex dimorphism of the renin-angiotensin-aldosterone system and, by extension, the mineralocorticoid receptor (MR) signaling pathway, major regulators of blood pressure, has only been poorly studied, notably in the kidney. Basal systolic blood pressure (SBP) and heart rate (HR) were measured in adult male and female mice. Renal gene expression studies o...