Searchable abstracts of presentations at key conferences in endocrinology

ea0035p1063 | Thyroid (non-cancer) | ECE2014

Inferior oblique muscle enlargement in a patient with Grave's orbitopathy

Tsirouki Theodora , Vasiliou Agathe , Koukoulis Georgios N , Tsironi Evaggelia , Kapsalaki Eftychia , Bargiota Alexandra

GravesÂ’ orbitopathy (GO) is an auto-immune disorder that targets intra-orbital tissues. It is well proven to involve inflammatory hypertrophy of the rectus EOMs. Superior oblique (SO) muscle has been sporadically reported to be involved in GO. However, there are extremely few reports in the literature that refer to the involvement of the inferior oblique (IO) muscle and here we present such a case.A 33-year-old man with unilateral exophthalmos was r...

ea0035p1066 | Thyroid (non-cancer) | ECE2014

MRI evaluation of extraocular muscles in patients with Grave's orbitopathy

Tsirouki Theodora , Valvis Nikolaos , Tsironi Evaggelia , Koukoulis Georgios N , Kapsalaki Eftychia , Bargiota Alexandra

Background: Clinical evaluation of GravesÂ’ orbitopathy (GO) is often insufficient. Frequently it is difficult to decide whether a case of GO is active, or to detect the degree of severity. STIR sequence MRI suppresses signal from fat and thus in the orbits can also detect active inflammation and oedema of extra-ocular muscles (EOMs). The aim of the present study is to examine whether imaging of rectus EOMs with STIR MRI could provide additional information for the activit...

ea0035p1054 | Thyroid (non-cancer) | ECE2014

Steroid treatment in patients with active moderate-to-severe Graves orbitopathy

Tsirouki Theodora , Giotaki Zoi , Rizoulis Andreas , Tigas Stelios , Asproudis Ioannis , Tsatsoulis Agathocles , Kapsalaki Eftychia , Tsironi Evaggelia , Koukoulis Georgios N , Bargiota Alexandra

Background: Although IV steroids are the treatment of choice for moderate-to-severe graves orbitopathy (M-S GO), the most efficacious regimen is not yet defined. Cases not responding or relapsing after steroid treatment (STx) are not uncommon and STx can cause serious adverse events. The aim of the present study is to define the steroid regimen which balances between efficacy and damage, using stir-sequence orbital-MRI (SsMRIo) as an additional objective tool for the evaluatio...